Genomic Adaption and Mutational Patterns in a HaCaT Subline Resistant to Alkylating Agents and Ionizing Radiation

Sulfur mustard (SM) is a chemical warfare agent that can damage DNA via alkylation and oxidative stress. Because of its genotoxicity, SM is cancerogenic and the progenitor of many chemotherapeutics. Previously, we developed an SM-resistant cell line via chronic exposure of the popular keratinocyte c...

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Detalles Bibliográficos
Autores principales: Ullmann, Reinhard, Becker, Benjamin Valentin, Rothmiller, Simone, Schmidt, Annette, Thiermann, Horst, Kaatsch, Hanns Leonhard, Schrock, Gerrit, Müller, Jessica, Jakobi, Julia, Obermair, Richard, Port, Matthias, Scherthan, Harry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865644/
https://www.ncbi.nlm.nih.gov/pubmed/33498964
http://dx.doi.org/10.3390/ijms22031146

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