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Click Conjugation of Boron Dipyrromethene (BODIPY) Fluorophores to EGFR-Targeting Linear and Cyclic Peptides

Through a simple 1,3-cycloaddition reaction, three BODIPY-peptide conjugates that target the extracellular domain of the epidermal growth factor receptor (EGFR) were prepared and their ability for binding to EGFR was investigated. The peptide ligands K(N(3))LARLLT and its cyclic analog cyclo(K(N(3))...

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Detalles Bibliográficos
Autores principales: Williams, Tyrslai M., Kaufman, Nichole E. M., Zhou, Zehua, Singh, Sitanshu S., Jois, Seetharama D., Vicente, Maria da Graça H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865655/
https://www.ncbi.nlm.nih.gov/pubmed/33498632
http://dx.doi.org/10.3390/molecules26030593

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