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3D Bioprinting of In Vitro Models Using Hydrogel-Based Bioinks

Coronavirus disease 2019 (COVID-19), which has recently emerged as a global pandemic, has caused a serious economic crisis due to the social disconnection and physical distancing in human society. To rapidly respond to the emergence of new diseases, a reliable in vitro model needs to be established...

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Autores principales: Choi, Yeong-Jin, Park, Honghyun, Ha, Dong-Heon, Yun, Hui-Suk, Yi, Hee-Gyeong, Lee, Hyungseok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865738/
https://www.ncbi.nlm.nih.gov/pubmed/33498852
http://dx.doi.org/10.3390/polym13030366
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author Choi, Yeong-Jin
Park, Honghyun
Ha, Dong-Heon
Yun, Hui-Suk
Yi, Hee-Gyeong
Lee, Hyungseok
author_facet Choi, Yeong-Jin
Park, Honghyun
Ha, Dong-Heon
Yun, Hui-Suk
Yi, Hee-Gyeong
Lee, Hyungseok
author_sort Choi, Yeong-Jin
collection PubMed
description Coronavirus disease 2019 (COVID-19), which has recently emerged as a global pandemic, has caused a serious economic crisis due to the social disconnection and physical distancing in human society. To rapidly respond to the emergence of new diseases, a reliable in vitro model needs to be established expeditiously for the identification of appropriate therapeutic agents. Such models can be of great help in validating the pathological behavior of pathogens and therapeutic agents. Recently, in vitro models representing human organs and tissues and biological functions have been developed based on high-precision 3D bioprinting. In this paper, we delineate an in-depth assessment of the recently developed 3D bioprinting technology and bioinks. In particular, we discuss the latest achievements and future aspects of the use of 3D bioprinting for in vitro modeling.
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spelling pubmed-78657382021-02-07 3D Bioprinting of In Vitro Models Using Hydrogel-Based Bioinks Choi, Yeong-Jin Park, Honghyun Ha, Dong-Heon Yun, Hui-Suk Yi, Hee-Gyeong Lee, Hyungseok Polymers (Basel) Review Coronavirus disease 2019 (COVID-19), which has recently emerged as a global pandemic, has caused a serious economic crisis due to the social disconnection and physical distancing in human society. To rapidly respond to the emergence of new diseases, a reliable in vitro model needs to be established expeditiously for the identification of appropriate therapeutic agents. Such models can be of great help in validating the pathological behavior of pathogens and therapeutic agents. Recently, in vitro models representing human organs and tissues and biological functions have been developed based on high-precision 3D bioprinting. In this paper, we delineate an in-depth assessment of the recently developed 3D bioprinting technology and bioinks. In particular, we discuss the latest achievements and future aspects of the use of 3D bioprinting for in vitro modeling. MDPI 2021-01-24 /pmc/articles/PMC7865738/ /pubmed/33498852 http://dx.doi.org/10.3390/polym13030366 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Choi, Yeong-Jin
Park, Honghyun
Ha, Dong-Heon
Yun, Hui-Suk
Yi, Hee-Gyeong
Lee, Hyungseok
3D Bioprinting of In Vitro Models Using Hydrogel-Based Bioinks
title 3D Bioprinting of In Vitro Models Using Hydrogel-Based Bioinks
title_full 3D Bioprinting of In Vitro Models Using Hydrogel-Based Bioinks
title_fullStr 3D Bioprinting of In Vitro Models Using Hydrogel-Based Bioinks
title_full_unstemmed 3D Bioprinting of In Vitro Models Using Hydrogel-Based Bioinks
title_short 3D Bioprinting of In Vitro Models Using Hydrogel-Based Bioinks
title_sort 3d bioprinting of in vitro models using hydrogel-based bioinks
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865738/
https://www.ncbi.nlm.nih.gov/pubmed/33498852
http://dx.doi.org/10.3390/polym13030366
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