Cargando…
3D Bioprinting of In Vitro Models Using Hydrogel-Based Bioinks
Coronavirus disease 2019 (COVID-19), which has recently emerged as a global pandemic, has caused a serious economic crisis due to the social disconnection and physical distancing in human society. To rapidly respond to the emergence of new diseases, a reliable in vitro model needs to be established...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865738/ https://www.ncbi.nlm.nih.gov/pubmed/33498852 http://dx.doi.org/10.3390/polym13030366 |
_version_ | 1783647917207191552 |
---|---|
author | Choi, Yeong-Jin Park, Honghyun Ha, Dong-Heon Yun, Hui-Suk Yi, Hee-Gyeong Lee, Hyungseok |
author_facet | Choi, Yeong-Jin Park, Honghyun Ha, Dong-Heon Yun, Hui-Suk Yi, Hee-Gyeong Lee, Hyungseok |
author_sort | Choi, Yeong-Jin |
collection | PubMed |
description | Coronavirus disease 2019 (COVID-19), which has recently emerged as a global pandemic, has caused a serious economic crisis due to the social disconnection and physical distancing in human society. To rapidly respond to the emergence of new diseases, a reliable in vitro model needs to be established expeditiously for the identification of appropriate therapeutic agents. Such models can be of great help in validating the pathological behavior of pathogens and therapeutic agents. Recently, in vitro models representing human organs and tissues and biological functions have been developed based on high-precision 3D bioprinting. In this paper, we delineate an in-depth assessment of the recently developed 3D bioprinting technology and bioinks. In particular, we discuss the latest achievements and future aspects of the use of 3D bioprinting for in vitro modeling. |
format | Online Article Text |
id | pubmed-7865738 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-78657382021-02-07 3D Bioprinting of In Vitro Models Using Hydrogel-Based Bioinks Choi, Yeong-Jin Park, Honghyun Ha, Dong-Heon Yun, Hui-Suk Yi, Hee-Gyeong Lee, Hyungseok Polymers (Basel) Review Coronavirus disease 2019 (COVID-19), which has recently emerged as a global pandemic, has caused a serious economic crisis due to the social disconnection and physical distancing in human society. To rapidly respond to the emergence of new diseases, a reliable in vitro model needs to be established expeditiously for the identification of appropriate therapeutic agents. Such models can be of great help in validating the pathological behavior of pathogens and therapeutic agents. Recently, in vitro models representing human organs and tissues and biological functions have been developed based on high-precision 3D bioprinting. In this paper, we delineate an in-depth assessment of the recently developed 3D bioprinting technology and bioinks. In particular, we discuss the latest achievements and future aspects of the use of 3D bioprinting for in vitro modeling. MDPI 2021-01-24 /pmc/articles/PMC7865738/ /pubmed/33498852 http://dx.doi.org/10.3390/polym13030366 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Choi, Yeong-Jin Park, Honghyun Ha, Dong-Heon Yun, Hui-Suk Yi, Hee-Gyeong Lee, Hyungseok 3D Bioprinting of In Vitro Models Using Hydrogel-Based Bioinks |
title | 3D Bioprinting of In Vitro Models Using Hydrogel-Based Bioinks |
title_full | 3D Bioprinting of In Vitro Models Using Hydrogel-Based Bioinks |
title_fullStr | 3D Bioprinting of In Vitro Models Using Hydrogel-Based Bioinks |
title_full_unstemmed | 3D Bioprinting of In Vitro Models Using Hydrogel-Based Bioinks |
title_short | 3D Bioprinting of In Vitro Models Using Hydrogel-Based Bioinks |
title_sort | 3d bioprinting of in vitro models using hydrogel-based bioinks |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865738/ https://www.ncbi.nlm.nih.gov/pubmed/33498852 http://dx.doi.org/10.3390/polym13030366 |
work_keys_str_mv | AT choiyeongjin 3dbioprintingofinvitromodelsusinghydrogelbasedbioinks AT parkhonghyun 3dbioprintingofinvitromodelsusinghydrogelbasedbioinks AT hadongheon 3dbioprintingofinvitromodelsusinghydrogelbasedbioinks AT yunhuisuk 3dbioprintingofinvitromodelsusinghydrogelbasedbioinks AT yiheegyeong 3dbioprintingofinvitromodelsusinghydrogelbasedbioinks AT leehyungseok 3dbioprintingofinvitromodelsusinghydrogelbasedbioinks |