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Structural Impacts of Drug-Resistance Mutations Appearing in HIV-2 Protease

The use of antiretroviral drugs is accompanied by the emergence of HIV-2 resistances. Thus, it is important to elucidate the mechanisms of resistance to antiretroviral drugs. Here, we propose a structural analysis of 31 drug-resistant mutants of HIV-2 protease (PR2) that is an important target again...

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Detalles Bibliográficos
Autores principales:	Laville, Pierre, Petitjean, Michel, Regad, Leslie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865771/ https://www.ncbi.nlm.nih.gov/pubmed/33503916 http://dx.doi.org/10.3390/molecules26030611

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