Diagnosis of Lynch Syndrome and Strategies to Distinguish Lynch-Related Tumors from Sporadic MSI/dMMR Tumors

SIMPLE SUMMARY: Microsatellite instability (MSI) is a hallmark of Lynch syndrome (LS)-related tumors but is not specific, as most of MSI/mismatch repair-deficient (dMMR) tumors are sporadic. Therefore, the identification of MSI/dMMR requires additional diagnostic tools to identify LS. In this review...

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Detalles Bibliográficos
Autores principales: Leclerc, Julie, Vermaut, Catherine, Buisine, Marie-Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865821/
https://www.ncbi.nlm.nih.gov/pubmed/33530449
http://dx.doi.org/10.3390/cancers13030467

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865821/
https://www.ncbi.nlm.nih.gov/pubmed/33530449
http://dx.doi.org/10.3390/cancers13030467

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