Cargando…

Role of NLRs in the Regulation of Type I Interferon Signaling, Host Defense and Tolerance to Inflammation

Type I interferon signaling contributes to the development of innate and adaptive immune responses to either viruses, fungi, or bacteria. However, amplitude and timing of the interferon response is of utmost importance for preventing an underwhelming outcome, or tissue damage. While several pathogen...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kienes, Ioannis, Weidl, Tanja, Mirza, Nora, Chamaillard, Mathias, Kufer, Thomas A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865845/ https://www.ncbi.nlm.nih.gov/pubmed/33525590 http://dx.doi.org/10.3390/ijms22031301

Ejemplares similares

DDX3X Links NLRP11 to the Regulation of Type I Interferon Responses and NLRP3 Inflammasome Activation
por: Kienes, Ioannis, et al.
Publicado: (2021)

How activated NLRs induce anti-microbial defenses in plants
por: El Kasmi, Farid
Publicado: (2021)

The Interplay between NLRs and Autophagy in Immunity and Inflammation
por: Carneiro, Leticia A. M., et al.
Publicado: (2013)

Non-Inflammasome Forming NLRs in Inflammation and Tumorigenesis
por: Allen, Irving Coy
Publicado: (2014)

Regulatory NLRs Control the RLR-Mediated Type I Interferon and Inflammatory Responses in Human Dendritic Cells
por: Fekete, Tünde, et al.
Publicado: (2018)

Innate immunity and transplantation tolerance: the potential role of TLRs/NLRs in GVHD
por: Shin, Ok S., et al.
Publicado: (2011)

XIAP controls RIPK2 signaling by preventing its deposition in speck-like structures
por: Ellwanger, Kornelia, et al.
Publicado: (2019)

Molecular insights into the biochemical functions and signalling mechanisms of plant NLRs
por: Liu, Xiaoxiao, et al.
Publicado: (2022)

Debug Your Bugs – How NLRs Shape Intestinal Host-Microbe Interactions
por: Lipinski, Simone, et al.
Publicado: (2013)

Beneficial and Detrimental Roles of NLRs in Carcinogenesis
por: Janowski, Ann M., et al.
Publicado: (2013)

Plant NLRs: The Whistleblowers of Plant Immunity
por: van Wersch, Solveig, et al.
Publicado: (2020)

Plant NLRs: The Whistleblowers of Plant Immunity
por: van Wersch, Solveig, et al.
Publicado: (2019)

The Many Faces of NLRs in Macrophage Biology
por: Frangogiannis, Nikolaos G.
Publicado: (2023)

Type I interferons drive inflammasome-independent emergency monocytopoiesis during endotoxemia
por: Lasseaux, Corentin, et al.
Publicado: (2017)

Negative regulatory NLRs mitigate inflammation via NF-κB pathway signaling in inflammatory bowel disease
por: Morrison, Holly A., et al.
Publicado: (2023)

NLRs: Sentinels of innate immunity or cancer culprits?
por: Correa, Ricardo G., et al.
Publicado: (2014)

Holding the Inflammatory System in Check: TLRs and NLRs
por: Holl, Eda K., et al.
Publicado: (2016)

Phagocyte Escape of Leptospira: The Role of TLRs and NLRs
por: Santecchia, Ignacio, et al.
Publicado: (2020)

Bacterial subversion of NLR-mediated immune responses
por: Kienes, Ioannis, et al.
Publicado: (2022)

An Integrated View of Deubiquitinating Enzymes Involved in Type I Interferon Signaling, Host Defense and Antiviral Activities
por: Qian, Guanghui, et al.
Publicado: (2021)

Toll-Like Receptors (TLRs), NOD-Like Receptors (NLRs), and RIG-I-Like Receptors (RLRs) in Innate Immunity. TLRs, NLRs, and RLRs Ligands as Immunotherapeutic Agents for Hematopoietic Diseases
por: Wicherska-Pawłowska, Katarzyna, et al.
Publicado: (2021)

The Complexity of Interferon Signaling in Host Defense against Protozoan Parasite Infection
por: Deng, Silu, et al.
Publicado: (2023)

Holding the inflammatory system in check: NLRs keep it cool
por: Jha, Sushmita, et al.
Publicado: (2015)

Inflammasome-independent functions of NAIPs and NLRs in the intestinal epithelium
por: Scarfe, Lisa, et al.
Publicado: (2021)

Diversification of defensins and NLRs in Arabidopsis species by different evolutionary mechanisms
por: Mondragón-Palomino, Mariana, et al.
Publicado: (2017)

Innate immune receptors for cross-presentation: The expanding role of NLRs
por: Corridoni, Daniele, et al.
Publicado: (2019)

Plant NLRs: Evolving with pathogen effectors and engineerable to improve resistance
por: Zhang, Biaoming, et al.
Publicado: (2022)

Lack of Type I Interferon Signaling Ameliorates Respiratory Syncytial Virus-Induced Lung Inflammation and Restores Antioxidant Defenses
por: Ansar, Maria, et al.
Publicado: (2021)

SOCS-1 inhibition of type I interferon restrains Staphylococcus aureus skin host defense
por: Klopfenstein, Nathan, et al.
Publicado: (2021)

Recognition of Extracellular Bacteria by NLRs and Its Role in the Development of Adaptive Immunity
por: Ferrand, Jonathan, et al.
Publicado: (2013)

Expression of urinary miRNAs targeting NLRs inflammasomes in bladder cancer
por: Mearini, Ettore, et al.
Publicado: (2017)

Host Defense and Tolerance: Unique Challenges in the Placenta
por: Zeldovich, Varvara B., et al.
Publicado: (2012)

Interferon Induced IFIT Family Genes in Host Antiviral Defense
por: Zhou, Xiang, et al.
Publicado: (2013)

The role of itaconate in host defense and inflammation
por: Peace, Christian G., et al.
Publicado: (2022)

Functional genomics identifies type I interferon pathway as central for host defense against Candida albicans
por: Smeekens, Sanne P., et al.
Publicado: (2013)

Cryptosporidium uses CSpV1 to activate host type I interferon and attenuate antiparasitic defenses
por: Deng, Silu, et al.
Publicado: (2023)

Regulating Caspase-1 During Infection: Roles of NLRs, AIM2, and ASC
por: Case, Christopher L.
Publicado: (2011)

IRGM1 supports host defense against intracellular bacteria through suppression of type I interferon in mice
por: Rai, Prashant, et al.
Publicado: (2023)

Annexin A2 in Inflammation and Host Defense
por: Dallacasagrande, Valentina, et al.
Publicado: (2020)

Antithrombin and Its Role in Host Defense and Inflammation
por: Schlömmer, Christine, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_58pj5fr9btt4it0e8mgv583013