Aptamers Against the β-Conglutin Allergen: Insights into the Behavior of the Shortest Multimeric(Intra)Molecular DNA G-Quadruplex

In previous work, a 93-mer aptamer was selected against the anaphylactic allergen, β-conglutin and truncated to an 11-mer, improving the affinity by two orders of magnitude, whilst maintaining the specificity. This 11-mer was observed to fold in a G-quadruplex, and preliminary results indicated the...

Descripción completa

Detalles Bibliográficos
Autores principales: O’ Sullivan, Ciara K., Mairal, Teresa, Jauset-Rubio, Miriam, Svobodova, Marketa, Skouridou, Vasso, Esposito, Veronica, Virgilio, Antonella, Galeone, Aldo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865891/
https://www.ncbi.nlm.nih.gov/pubmed/33498970
http://dx.doi.org/10.3390/ijms22031150

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865891/
https://www.ncbi.nlm.nih.gov/pubmed/33498970
http://dx.doi.org/10.3390/ijms22031150

Ejemplares similares