Nuclear Reorganization in Hippocampal Granule Cell Neurons from a Mouse Model of Down Syndrome: Changes in Chromatin Configuration, Nucleoli and Cajal Bodies

Down syndrome (DS) or trisomy of chromosome 21 (Hsa21) is characterized by impaired hippocampal-dependent learning and memory. These alterations are due to defective neurogenesis and to neuromorphological and functional anomalies of numerous neuronal populations, including hippocampal granular cells...

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Detalles Bibliográficos
Autores principales: Puente-Bedia, Alba, Berciano, María T., Tapia, Olga, Martínez-Cué, Carmen, Lafarga, Miguel, Rueda, Noemí
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865916/
https://www.ncbi.nlm.nih.gov/pubmed/33514010
http://dx.doi.org/10.3390/ijms22031259

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