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Therapeutic Application of Exosomes in Inflammatory Diseases

Immunomodulation is on the cusp of being an important therapy for treating many diseases, due to the significant role of the immune system in defending the human body. Although the immune system is an essential defense system, overactivity can result in diverse sicknesses such as inflammation and au...

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Detalles Bibliográficos
Autores principales: Suh, Ju Hun, Joo, Hyeon Su, Hong, Eun Be, Lee, Hyeon Ji, Lee, Jung Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865921/
https://www.ncbi.nlm.nih.gov/pubmed/33498928
http://dx.doi.org/10.3390/ijms22031144
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author Suh, Ju Hun
Joo, Hyeon Su
Hong, Eun Be
Lee, Hyeon Ji
Lee, Jung Min
author_facet Suh, Ju Hun
Joo, Hyeon Su
Hong, Eun Be
Lee, Hyeon Ji
Lee, Jung Min
author_sort Suh, Ju Hun
collection PubMed
description Immunomodulation is on the cusp of being an important therapy for treating many diseases, due to the significant role of the immune system in defending the human body. Although the immune system is an essential defense system, overactivity can result in diverse sicknesses such as inflammation and autoimmune disease. Exosomes are emerging as a state-of-the-art therapeutic strategy for treating an overactive immune system. Thus, in this review, we will thoroughly review therapeutic applications of exosomes in various inflammatory and autoimmune diseases. Finally, issues for an outlook to the future of exosomal therapy will be introduced.
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spelling pubmed-78659212021-02-07 Therapeutic Application of Exosomes in Inflammatory Diseases Suh, Ju Hun Joo, Hyeon Su Hong, Eun Be Lee, Hyeon Ji Lee, Jung Min Int J Mol Sci Review Immunomodulation is on the cusp of being an important therapy for treating many diseases, due to the significant role of the immune system in defending the human body. Although the immune system is an essential defense system, overactivity can result in diverse sicknesses such as inflammation and autoimmune disease. Exosomes are emerging as a state-of-the-art therapeutic strategy for treating an overactive immune system. Thus, in this review, we will thoroughly review therapeutic applications of exosomes in various inflammatory and autoimmune diseases. Finally, issues for an outlook to the future of exosomal therapy will be introduced. MDPI 2021-01-24 /pmc/articles/PMC7865921/ /pubmed/33498928 http://dx.doi.org/10.3390/ijms22031144 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Suh, Ju Hun
Joo, Hyeon Su
Hong, Eun Be
Lee, Hyeon Ji
Lee, Jung Min
Therapeutic Application of Exosomes in Inflammatory Diseases
title Therapeutic Application of Exosomes in Inflammatory Diseases
title_full Therapeutic Application of Exosomes in Inflammatory Diseases
title_fullStr Therapeutic Application of Exosomes in Inflammatory Diseases
title_full_unstemmed Therapeutic Application of Exosomes in Inflammatory Diseases
title_short Therapeutic Application of Exosomes in Inflammatory Diseases
title_sort therapeutic application of exosomes in inflammatory diseases
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865921/
https://www.ncbi.nlm.nih.gov/pubmed/33498928
http://dx.doi.org/10.3390/ijms22031144
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