Cargando…

How Should We Test for Lynch Syndrome? A Review of Current Guidelines and Future Strategies

SIMPLE SUMMARY: Carriers of Lynch syndrome (LS) have an increased risk for several types of tumour, in particular bowel and uterine cancers. LS is caused by inheritance of a faulty mismatch repair (MMR) gene, and, in accordance with clinical guidelines, bowel cancers are tested for MMR deficiency to...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gallon, Richard, Gawthorpe, Peter, Phelps, Rachel L., Hayes, Christine, Borthwick, Gillian M., Santibanez-Koref, Mauro, Jackson, Michael S., Burn, John
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7865939/ https://www.ncbi.nlm.nih.gov/pubmed/33499123 http://dx.doi.org/10.3390/cancers13030406

Ejemplares similares

Mismatch repair deficiency testing in Lynch syndrome-associated urothelial tumors
por: Rasmussen, Maria, et al.
Publicado: (2023)

Detection of Microsatellite Instability in Colonoscopic Biopsies and Postal Urine Samples from Lynch Syndrome Cancer Patients Using a Multiplex PCR Assay
por: Phelps, Rachel, et al.
Publicado: (2022)

Sebaceous tumours: a prototypical class of skin tumour for universal germline genetic testing
por: Gallon, R., et al.
Publicado: (2021)

Sequencing‐based microsatellite instability testing using as few as six markers for high‐throughput clinical diagnostics
por: Gallon, Richard, et al.
Publicado: (2019)

Future collapse: how optimistic should we be?
por: Ehrlich, Paul R., et al.
Publicado: (2013)

Association of stroke and bleed events in non-valvular atrial fibrillation patients with direct oral anticoagulant prescriptions in NHS England between 2013 and 2016
por: Sheth, Harsh, et al.
Publicado: (2019)

Testing Women With Endometrial Cancer for Lynch Syndrome: Should We Test All?
por: Ma, Jun, et al.
Publicado: (2013)

Constitutional mismatch repair deficiency is the diagnosis in 0.41% of pathogenic NF1/SPRED1 variant negative children suspected of sporadic neurofibromatosis type 1
por: Perez-Valencia, Juan A., et al.
Publicado: (2020)

Chromosome 9p21 SNPs Associated with Multiple Disease Phenotypes Correlate with ANRIL Expression
por: Cunnington, Michael S., et al.
Publicado: (2010)

Is there evidence that we should screen the general population for Lynch syndrome with genetic testing? A systematic review
por: Prince, Anya E R, et al.
Publicado: (2017)

How far should guidelines be followed?
por: Rapezzi, Claudio, et al.
Publicado: (2020)

Anticipation in Lynch Syndrome: Where We Are Where We Go
por: Bozzao, Cristina, et al.
Publicado: (2011)

How do we and how should we deal with uncertainty in endodontics?
por: Pigg, Maria, et al.
Publicado: (2022)

How Should we Handle Safety?
por: Albert, M, et al.
Publicado: (2001)

How Should We Manage Myelofibrosis?
por: Pegrum, G. D., et al.
Publicado: (1981)

NSTEMI treatment: should we always follow the guidelines?
por: van ’t Hof, A. W. J., et al.
Publicado: (2019)

How the nursing profession should adapt for a digital future
por: Booth, Richard G, et al.
Publicado: (2021)

European guidelines from the EHTG and ESCP for Lynch syndrome: an updated third edition of the Mallorca guidelines based on gene and gender
por: Seppälä, T T, et al.
Publicado: (2021)

Noninvasive ventilation for acute lung injury: how often should we try, how often should we fail?
por: Garpestad, Erik, et al.
Publicado: (2006)

Should we treat pyrexia? And how do we do it?
por: Doyle, James F., et al.
Publicado: (2016)

How Should We Approach Syncope in the Emergency Department? Current Perspectives
por: Canakci, Mustafa Emin, et al.
Publicado: (2022)

A novel panel of short mononucleotide repeats linked to informative polymorphisms enabling effective high volume low cost discrimination between mismatch repair deficient and proficient tumours
por: Redford, Lisa, et al.
Publicado: (2018)

How Should We Organize the Higgs Safari?
por: Janot, P
Publicado: (1999)

How should we address the pipeline problem?
por: Braun, Hillary J.
Publicado: (2016)

Elastomeric pumps: How cautious should we be?
por: Ray, Swarup, et al.
Publicado: (2018)

How Should We Classify Kawasaki Disease?
por: Marrani, Edoardo, et al.
Publicado: (2018)

FMT in IBS: how cautious should we be?
por: El-Salhy, Magdy
Publicado: (2021)

How should we conduct pandemic vaccination?
por: Williams, Jane, et al.
Publicado: (2021)

Should we reconsider how to assess eutrophication?
por: Polimene, L, et al.
Publicado: (2023)

How should humanity steer the future?
por: Aguirre, Anthony, et al.
Publicado: (2016)

Analysis of human ES cell differentiation establishes that the dominant isoforms of the lncRNAs RMST and FIRRE are circular
por: Izuogu, Osagie G., et al.
Publicado: (2018)

How should activity guidelines for young people be operationalised?
por: Olds, Tim, et al.
Publicado: (2007)

Human Chondrocytes Respond Discordantly to the Protein Encoded by the Osteoarthritis Susceptibility Gene GDF5
por: Ratnayake, Madhushika, et al.
Publicado: (2014)

Circulating cell-free mitochondrial DNA levels in Parkinson’s disease are influenced by treatment
por: Lowes, Hannah, et al.
Publicado: (2020)

Genetic testing and research in Lynch Syndrome - is it a choice or a responsibility?
por: Cowley, Lorraine, et al.
Publicado: (2011)

Oestrogen receptor beta: how should we measure this?
por: Speirs, V, et al.
Publicado: (2002)

How should we describe the benefits of palliative radiotherapy?
por: Samant, R., et al.
Publicado: (2006)

How should we intervene in psychosis risk syndromes?
por: Wang, Jijun, et al.
Publicado: (2013)

How should we be selecting our graduate students?
por: Weiner, Orion D.
Publicado: (2014)

How and why should we implement genomics into conservation?
por: McMahon, Barry J, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_7ek3sqidg46ndol48gf5qod1k1