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In Silico Assessment of Class I Antiarrhythmic Drug Effects on Pitx2-Induced Atrial Fibrillation: Insights from Populations of Electrophysiological Models of Human Atrial Cells and Tissues

Electrical remodelling as a result of homeodomain transcription factor 2 (Pitx2)-dependent gene regulation was linked to atrial fibrillation (AF) and AF patients with single nucleotide polymorphisms at chromosome 4q25 responded favorably to class I antiarrhythmic drugs (AADs). The possible reasons b...

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Detalles Bibliográficos
Autores principales:	Bai, Jieyun, Zhu, Yijie, Lo, Andy, Gao, Meng, Lu, Yaosheng, Zhao, Jichao, Zhang, Henggui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7866025/ https://www.ncbi.nlm.nih.gov/pubmed/33514068 http://dx.doi.org/10.3390/ijms22031265

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