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Characterization of Bio-Inspired Electro-Conductive Soy Protein Films

Protein-based conductive materials are gaining attention as alternative components of electronic devices for value-added applications. In this regard, soy protein isolate (SPI) was processed by extrusion in order to obtain SPI pellets, subsequently molded into SPI films by hot pressing, resulting in...

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Autores principales: Guerrero, Pedro, Garrido, Tania, Garcia-Orue, Itxaso, Santos-Vizcaino, Edorta, Igartua, Manoli, Hernandez, Rosa Maria, de la Caba, Koro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7866128/
https://www.ncbi.nlm.nih.gov/pubmed/33525478
http://dx.doi.org/10.3390/polym13030416
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author Guerrero, Pedro
Garrido, Tania
Garcia-Orue, Itxaso
Santos-Vizcaino, Edorta
Igartua, Manoli
Hernandez, Rosa Maria
de la Caba, Koro
author_facet Guerrero, Pedro
Garrido, Tania
Garcia-Orue, Itxaso
Santos-Vizcaino, Edorta
Igartua, Manoli
Hernandez, Rosa Maria
de la Caba, Koro
author_sort Guerrero, Pedro
collection PubMed
description Protein-based conductive materials are gaining attention as alternative components of electronic devices for value-added applications. In this regard, soy protein isolate (SPI) was processed by extrusion in order to obtain SPI pellets, subsequently molded into SPI films by hot pressing, resulting in homogeneous and transparent films, as shown by scanning electron microscopy and UV-vis spectroscopy analyses, respectively. During processing, SPI denatured and refolded through intermolecular interactions with glycerol, causing a major exposition of tryptophan residues and fluorescence emission, affecting charge distribution and electron transport properties. Regarding electrical conductivity, the value found (9.889 × 10(−4) S/m) is characteristic of electrical semiconductors, such as silicon, and higher than that found for other natural polymers. Additionally, the behavior of the films in contact with water was analyzed, indicating a controlled swelling and a hydrolytic surface, which is of great relevance for cell adhesion and spreading. In fact, cytotoxicity studies showed that the developed SPI films were biocompatible, according to the guidelines for the biological evaluation of medical devices. Therefore, these SPI films are uniquely suited as bioelectronics because they conduct both ionic and electronic currents, which is not accessible for the traditional metallic conductors.
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spelling pubmed-78661282021-02-07 Characterization of Bio-Inspired Electro-Conductive Soy Protein Films Guerrero, Pedro Garrido, Tania Garcia-Orue, Itxaso Santos-Vizcaino, Edorta Igartua, Manoli Hernandez, Rosa Maria de la Caba, Koro Polymers (Basel) Article Protein-based conductive materials are gaining attention as alternative components of electronic devices for value-added applications. In this regard, soy protein isolate (SPI) was processed by extrusion in order to obtain SPI pellets, subsequently molded into SPI films by hot pressing, resulting in homogeneous and transparent films, as shown by scanning electron microscopy and UV-vis spectroscopy analyses, respectively. During processing, SPI denatured and refolded through intermolecular interactions with glycerol, causing a major exposition of tryptophan residues and fluorescence emission, affecting charge distribution and electron transport properties. Regarding electrical conductivity, the value found (9.889 × 10(−4) S/m) is characteristic of electrical semiconductors, such as silicon, and higher than that found for other natural polymers. Additionally, the behavior of the films in contact with water was analyzed, indicating a controlled swelling and a hydrolytic surface, which is of great relevance for cell adhesion and spreading. In fact, cytotoxicity studies showed that the developed SPI films were biocompatible, according to the guidelines for the biological evaluation of medical devices. Therefore, these SPI films are uniquely suited as bioelectronics because they conduct both ionic and electronic currents, which is not accessible for the traditional metallic conductors. MDPI 2021-01-28 /pmc/articles/PMC7866128/ /pubmed/33525478 http://dx.doi.org/10.3390/polym13030416 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Guerrero, Pedro
Garrido, Tania
Garcia-Orue, Itxaso
Santos-Vizcaino, Edorta
Igartua, Manoli
Hernandez, Rosa Maria
de la Caba, Koro
Characterization of Bio-Inspired Electro-Conductive Soy Protein Films
title Characterization of Bio-Inspired Electro-Conductive Soy Protein Films
title_full Characterization of Bio-Inspired Electro-Conductive Soy Protein Films
title_fullStr Characterization of Bio-Inspired Electro-Conductive Soy Protein Films
title_full_unstemmed Characterization of Bio-Inspired Electro-Conductive Soy Protein Films
title_short Characterization of Bio-Inspired Electro-Conductive Soy Protein Films
title_sort characterization of bio-inspired electro-conductive soy protein films
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7866128/
https://www.ncbi.nlm.nih.gov/pubmed/33525478
http://dx.doi.org/10.3390/polym13030416
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