JAK2 Inhibition by Fedratinib Reduces Osteoblast Differentiation and Mineralisation of Human Mesenchymal Stem Cells

Several signalling pathways, including the JAK/STAT signalling pathway, have been identified to regulate the differentiation of human bone marrow skeletal (mesenchymal) stem cells (hBMSCs) into bone-forming osteoblasts. Members of the JAK family mediate the intracellular signalling of various of cyt...

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Detalles Bibliográficos
Autores principales: AlMuraikhi, Nihal, Alaskar, Hanouf, Binhamdan, Sarah, Alotaibi, Amal, Kassem, Moustapha, Alfayez, Musaad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7866227/
https://www.ncbi.nlm.nih.gov/pubmed/33503825
http://dx.doi.org/10.3390/molecules26030606

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7866227/
https://www.ncbi.nlm.nih.gov/pubmed/33503825
http://dx.doi.org/10.3390/molecules26030606

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