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Laccase-Catalyzed 1,4-Dioxane-Mediated Synthesis of Belladine N-Oxides with Anti-Influenza A Virus Activity

Belladine N-oxides active against influenza A virus have been synthetized by a novel laccase-catalyzed 1,4-dioxane-mediated oxidation of aromatic and side-chain modified belladine derivatives. Electron paramagnetic resonance (EPR) analysis confirmed the role of 1,4-dioxane as a co-oxidant. The react...

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Detalles Bibliográficos
Autores principales:	Zippilli, Claudio, Botta, Lorenzo, Bizzarri, Bruno Mattia, Nencioni, Lucia, De Angelis, Marta, Protto, Virginia, Giorgi, Gianluca, Baratto, Maria Camilla, Pogni, Rebecca, Saladino, Raffaele
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7866262/ https://www.ncbi.nlm.nih.gov/pubmed/33572794 http://dx.doi.org/10.3390/ijms22031337

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