Exploiting Gangliosides for the Therapy of Ewing’s Sarcoma and H3K27M-Mutant Diffuse Midline Glioma

SIMPLE SUMMARY: Osteosarcoma, Ewing’s sarcoma, and H3K27M-mutant diffuse midline glioma are rare but aggressive malignancies occurring mainly in children. Due to their rareness and often fatal course, drug development is challenging. Here, we repurposed the existing drugs dinutuximab and eliglustat...

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Detalles Bibliográficos
Autores principales: Wingerter, Arthur, El Malki, Khalifa, Sandhoff, Roger, Seidmann, Larissa, Wagner, Daniel-Christoph, Lehmann, Nadine, Vewinger, Nadine, Frauenknecht, Katrin B. M., Sommer, Clemens J., Traub, Frank, Kindler, Thomas, Russo, Alexandra, Otto, Henrike, Lollert, André, Staatz, Gundula, Roth, Lea, Paret, Claudia, Faber, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7866294/
https://www.ncbi.nlm.nih.gov/pubmed/33572900
http://dx.doi.org/10.3390/cancers13030520

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