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In vivo tau pathology is associated with synaptic loss and altered synaptic function
BACKGROUND: The mechanism of synaptic loss in Alzheimer’s disease is poorly understood and may be associated with tau pathology. In this combined positron emission tomography (PET) and magnetoencephalography (MEG) study, we aimed to investigate spatial associations between regional tau pathology ([(...
Autores principales: | Coomans, Emma M., Schoonhoven, Deborah N., Tuncel, Hayel, Verfaillie, Sander C. J., Wolters, Emma E., Boellaard, Ronald, Ossenkoppele, Rik, den Braber, Anouk, Scheper, Wiep, Schober, Patrick, Sweeney, Steven P., Ryan, J. Michael, Schuit, Robert C., Windhorst, Albert D., Barkhof, Frederik, Scheltens, Philip, Golla, Sandeep S. V., Hillebrand, Arjan, Gouw, Alida A., van Berckel, Bart N. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7866464/ https://www.ncbi.nlm.nih.gov/pubmed/33546722 http://dx.doi.org/10.1186/s13195-021-00772-0 |
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