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Genetic Variants of ANGPT1, CD39, FGF2 and MMP9 Linked to Clinical Outcome of Bevacizumab Plus Chemotherapy for Metastatic Colorectal Cancer
Angiogenesis pathway genes show substantial genetic variability causing inter-individual differences in responses to anti-angiogenic drugs. We examined 20 single nucleotide polymorphisms (SNPs) in 13 of these genes to predict tumour response and clinical outcome measured as progression free survival...
Autores principales: | Gaibar, María, Galán, Miguel, Romero-Lorca, Alicia, Antón, Beatriz, Malón, Diego, Moreno, Amalia, Fernández-Santander, Ana, Novillo, Apolonia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7866547/ https://www.ncbi.nlm.nih.gov/pubmed/33573134 http://dx.doi.org/10.3390/ijms22031381 |
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