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pH-responsive delivery vehicle based on RGD-modified polydopamine-paclitaxel-loaded poly (3-hydroxybutyrate-co-3-hydroxyvalerate) nanoparticles for targeted therapy in hepatocellular carcinoma

A limitation of current anticancer nanocarriers is the contradiction between multiple functions and favorable biocompatibility. Thus, we aimed to develop a compatible drug delivery system loaded with paclitaxel (PTX) for hepatocellular carcinoma (HCC) therapy. A basic backbone, PTX-loaded poly (3-hy...

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Detalles Bibliográficos
Autores principales: Wu, Mingfang, Zhong, Chen, Zhang, Qian, Wang, Lu, Wang, Lingling, Liu, Yanjie, Zhang, Xiaoxue, Zhao, Xiuhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7866683/
https://www.ncbi.nlm.nih.gov/pubmed/33549107
http://dx.doi.org/10.1186/s12951-021-00783-x

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