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Abnormal electrophysiological phenotypes and sleep deficits in a mouse model of Angelman Syndrome
BACKGROUND: Angelman Syndrome (AS) is a rare genetic disorder characterized by impaired communication, motor and balance deficits, intellectual disabilities, recurring seizures and abnormal sleep patterns. The genetic cause of AS is neuronal-specific loss of expression of UBE3A (ubiquitin-protein li...
Autores principales: | Copping, N. A., Silverman, J. L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7866697/ https://www.ncbi.nlm.nih.gov/pubmed/33549123 http://dx.doi.org/10.1186/s13229-021-00416-y |
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