Whole-exome sequencing identifies novel mutations in ABC transporter genes associated with intrahepatic cholestasis of pregnancy disease: a case-control study

BACKGROUND: Intrahepatic cholestasis of pregnancy (ICP) can cause premature delivery and stillbirth. Previous studies have reported that mutations in ABC transporter genes strongly influence the transport of bile salts. However, to date, their effects are still largely elusive. METHODS: A whole-exom...

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Detalles Bibliográficos
Autores principales: Liu, Xianxian, Lai, Hua, Xin, Siming, Li, Zengming, Zeng, Xiaoming, Nie, Liju, Liang, Zhengyi, Wu, Meiling, Zheng, Jiusheng, Zou, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7866704/
https://www.ncbi.nlm.nih.gov/pubmed/33546617
http://dx.doi.org/10.1186/s12884-021-03595-x

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