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The lncRNA NEAT1 promotes the epithelial-mesenchymal transition and metastasis of osteosarcoma cells by sponging miR-483 to upregulate STAT3 expression
BACKGROUND: Osteosarcoma is one of the most prevalent primary bone tumours in adolescents. Accumulating evidence shows that aberrant expression of the long non-coding RNA (lncRNA) NEAT1 and microRNA-483 (miR-483) contribute to the epithelial-mesenchymal transition (EMT), invasion and metastasis of t...
Autores principales: | Chen, Yan, Li, Jun, Xiao, Jia-Kun, Xiao, Lei, Xu, Bin-Wu, Li, Chen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7866772/ https://www.ncbi.nlm.nih.gov/pubmed/33546665 http://dx.doi.org/10.1186/s12935-021-01780-8 |
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