The Origin of Tumor DNA in Urine of Urogenital Cancer Patients: Local Shedding and Transrenal Excretion

SIMPLE SUMMARY: There is a clinical need for non-invasive methods to detect urogenital cancer, for which urine offers a promising liquid biopsy. Tumor DNA in urine originates from shedding of the local tumor, but may also be excreted transrenally as circulating DNA fragments from the bloodstream. To...

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Detalles Bibliográficos
Autores principales: Hentschel, Anouk E., van den Helder, Rianne, van Trommel, Nienke E., van Splunter, Annina P., van Boerdonk, Robert A. A., van Gent, Mignon D. J. M., Nieuwenhuijzen, Jakko A., Steenbergen, Renske D. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7866784/
https://www.ncbi.nlm.nih.gov/pubmed/33572525
http://dx.doi.org/10.3390/cancers13030535

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