IGF-1 Upregulates Biglycan and Decorin by Increasing Translation and Reducing ADAMTS5 Expression

Proteoglycan (PG) is a glycosaminoglycan (GAG)-conjugated protein essential for maintaining tissue strength and elasticity. The most abundant skin PGs, biglycan and decorin, have been reported to decrease as skin ages. Insulin-like growth factor-1 (IGF-1) is important in various physiological functi...

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Detalles Bibliográficos
Autores principales: Lee, Hanon, Lim, Jiyeong, Oh, Jang-Hee, Cho, Soyun, Chung, Jin Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7866853/
https://www.ncbi.nlm.nih.gov/pubmed/33573338
http://dx.doi.org/10.3390/ijms22031403

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7866853/
https://www.ncbi.nlm.nih.gov/pubmed/33573338
http://dx.doi.org/10.3390/ijms22031403

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