Cargando…

Roles of CNC Transcription Factors NRF1 and NRF2 in Cancer

SIMPLE SUMMARY: Although NRF1 (nuclear factor erythroid 2-like 1; NFE2L1) and NRF2 (nuclear factor erythroid 2-like 2; NFE2L2) belong to the CNC (cap‘n’collar) transcription factor family and share DNA recognition elements, their functions in vivo are substantially different. In cancer cells, while...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sekine, Hiroki, Motohashi, Hozumi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7867063/ https://www.ncbi.nlm.nih.gov/pubmed/33535386 http://dx.doi.org/10.3390/cancers13030541

Ejemplares similares

Structural basis of transcription regulation by CNC family transcription factor, Nrf2
por: Sengoku, Toru, et al.
Publicado: (2022)

NRF2 addiction in cancer cells
por: Kitamura, Hiroshi, et al.
Publicado: (2018)

The KEAP1-NRF2 System in Healthy Aging and Longevity
por: Matsumaru, Daisuke, et al.
Publicado: (2021)

Metabolic features of cancer cells in NRF2 addiction status
por: Okazaki, Keito, et al.
Publicado: (2020)

Contribution of NRF2 to sulfur metabolism and mitochondrial activity
por: Alam, Md Morshedul, et al.
Publicado: (2023)

Nrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription
por: Kobayashi, Eri H., et al.
Publicado: (2016)

Sesamin Activates Nrf2/Cnc-Dependent Transcription in the Absence of Oxidative Stress in Drosophila Adult Brains
por: Le, Tuan Dat, et al.
Publicado: (2021)

The Keap1–Nrf2 system in cancers: stress response and anabolic metabolism
por: Mitsuishi, Yoichiro, et al.
Publicado: (2012)

The Nrf1 CNC-bZIP Protein Is Regulated by the Proteasome and Activated by Hypoxia
por: Chepelev, Nikolai L., et al.
Publicado: (2011)

O-GlcNAcylation Signal Mediates Proteasome Inhibitor Resistance in Cancer Cells by Stabilizing NRF1
por: Sekine, Hiroki, et al.
Publicado: (2018)

The anti-inflammatory and anti-oxidative effect of a classical hypnotic bromovalerylurea mediated by the activation of NRF2
por: Takeda, Haruna, et al.
Publicado: (2023)

The role of transcription factor Nrf2 in skin cells metabolism
por: Gęgotek, Agnieszka, et al.
Publicado: (2015)

NRF2 pathway activation by KEAP1 inhibition attenuates the manifestation of aging phenotypes in salivary glands
por: Wati, Sisca Meida, et al.
Publicado: (2020)

Defining the Functional Targets of Cap‘n’collar Transcription Factors NRF1, NRF2, and NRF3
por: Ibrahim, Lara, et al.
Publicado: (2020)

The Role of the Transcription Factor Nrf2 in Alzheimer’s Disease: Therapeutic Opportunities
por: De Plano, Laura Maria, et al.
Publicado: (2023)

Nrf1 and Nrf2 Transcription Factors Regulate Androgen Receptor Transactivation in Prostate Cancer Cells
por: Schultz, Michelle A., et al.
Publicado: (2014)

Role of NRF2 in Lung Cancer
por: Sánchez-Ortega, Miriam, et al.
Publicado: (2021)

Role of Nrf2 in Pancreatic Cancer
por: Cykowiak, Marta, et al.
Publicado: (2021)

Role of NRF2 in Ovarian Cancer
por: Tossetta, Giovanni, et al.
Publicado: (2022)

Transcriptional Regulation by Nrf2
por: Tonelli, Claudia, et al.
Publicado: (2018)

NRF2, a Transcription Factor for Stress Response and Beyond
por: He, Feng, et al.
Publicado: (2020)

Transcriptional regulation of the 26S proteasome by Nrf1
por: KOIZUMI, Shun, et al.
Publicado: (2018)

Progressive Rotavirus Infection Downregulates Redox-Sensitive Transcription Factor Nrf2 and Nrf2-Driven Transcription Units
por: Patra, Upayan, et al.
Publicado: (2020)

The Antioxidant Transcription Factor Nrf2 in Cardiac Ischemia–Reperfusion Injury
por: Mata, Ana, et al.
Publicado: (2021)

Enhancer remodeling promotes tumor-initiating activity in NRF2-activated non-small cell lung cancers
por: Okazaki, Keito, et al.
Publicado: (2020)

Competition of nuclear factor-erythroid 2 factors related transcription factor isoforms, Nrf1 and Nrf2, in antioxidant enzyme induction()
por: Chepelev, Nikolai L., et al.
Publicado: (2013)

Phenethyl Isothiocyanate, a Dual Activator of Transcription Factors NRF2 and HSF1
por: Dayalan Naidu, Sharadha, et al.
Publicado: (2018)

The Role of NRF2 in Mycobacterial Infection
por: Matsuyama, Masashi, et al.
Publicado: (2021)

Role of Nrf2 in bone metabolism
por: Sun, Yong-Xin, et al.
Publicado: (2015)

Activation of the NRF2 pathway in Keap1-knockdown mice attenuates progression of age-related hearing loss
por: Oishi, Tetsuya, et al.
Publicado: (2020)

The Role of Nrf2 Activity in Cancer Development and Progression
por: Zimta, Alina-Andreea, et al.
Publicado: (2019)

Role of NRF2 in Colorectal Cancer Prevention and Treatment
por: Li, Jiaxiang, et al.
Publicado: (2022)

Modulation of proteostasis by transcription factor NRF2 and impact in neurodegenerative diseases
por: Pajares, Marta, et al.
Publicado: (2017)

The C-Terminal Domain of Nrf1 Negatively Regulates the Full-Length CNC-bZIP Factor and Its Shorter Isoform LCR-F1/Nrf1β; Both Are Also Inhibited by the Small Dominant-Negative Nrf1γ/δ Isoforms that Down-Regulate ARE-Battery Gene Expression
por: Zhang, Yiguo, et al.
Publicado: (2014)

The Nrf1 and Nrf2 Balance in Oxidative Stress Regulation and Androgen Signaling in Prostate Cancer Cells
por: Schultz, Michelle A., et al.
Publicado: (2010)

The Role of NRF2/KEAP1 Signaling Pathway in Cancer Metabolism
por: Song, Moon-Young, et al.
Publicado: (2021)

The emerging role of the Nrf2–Keap1 signaling pathway in cancer
por: Jaramillo, Melba C., et al.
Publicado: (2013)

The Role of NRF2 in Obesity-Associated Cardiovascular Risk Factors
por: Gutiérrez-Cuevas, Jorge, et al.
Publicado: (2022)

ER-Resident Transcription Factor Nrf1 Regulates Proteasome Expression and Beyond
por: Hamazaki, Jun, et al.
Publicado: (2020)

Regulation of Wound Healing by the NRF2 Transcription Factor—More Than Cytoprotection
por: Hiebert, Paul, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_8hfjtvb1g08cs3952gfterr9ao