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A Bioassay Using a Pentadecanal Derivative to Measure S1P Lyase Activity

Sphingosine-1-phosphate (S1P) is a unique lipid ligand binding to S1P receptors to transduce various cell survival or proliferation signals via small G proteins. S1P lyase (S1PL) is the specific enzyme that degrades S1P to phosphoethanolamine and (2E)-hexadecenal and therefore regulates S1P levels....

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Detalles Bibliográficos
Autores principales: Shin, Kyong-Oh, Shamshiddinova, Maftuna, Lee, Jung-No, Lee, Kwang-Sik, Lee, Yong-Moon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7867068/
https://www.ncbi.nlm.nih.gov/pubmed/33535437
http://dx.doi.org/10.3390/ijms22031438