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Intricacies of GABA(A) Receptor Function: The Critical Role of the β3 Subunit in Norm and Pathology

Neuronal intracellular chloride ([Cl(−)](i)) is a key determinant in γ-aminobutyric acid type A (GABA)ergic signaling. γ-Aminobutyric acid type A receptors (GABA(A)Rs) mediate both inhibitory and excitatory neurotransmission, as the passive fluxes of Cl(−) and HCO(3)(−) via pores can be reversed by...

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Detalles Bibliográficos
Autores principales: Menzikov, Sergey A., Morozov, Sergey G., Kubatiev, Aslan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7867123/
https://www.ncbi.nlm.nih.gov/pubmed/33535681
http://dx.doi.org/10.3390/ijms22031457

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