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ESR1 NAPA Assay: Development and Analytical Validation of a Highly Sensitive and Specific Blood-Based Assay for the Detection of ESR1 Mutations in Liquid Biopsies

SIMPLE SUMMARY: A considerable number of estrogen-receptor–positive (ER+) breast cancer patients develop resistance to endocrine treatment. One of the most important resistance mechanisms is the presence of ESR1 mutations. In the present study, we developed and analytically validated a novel, highly...

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Detalles Bibliográficos
Autores principales:	Stergiopoulou, Dimitra, Markou, Athina, Tzanikou, Eleni, Ladas, Ioannis, Makrigiorgos, G. Mike, Georgoulias, Vassilis, Lianidou, Evi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7867152/ https://www.ncbi.nlm.nih.gov/pubmed/33535614 http://dx.doi.org/10.3390/cancers13030556

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