Cargando…

Low-Intensity Resistance Training with Moderate Blood Flow Restriction Appears Safe and Increases Skeletal Muscle Strength and Size in Cardiovascular Surgery Patients: A Pilot Study

We examined the safety and the effects of low-intensity resistance training (RT) with moderate blood flow restriction (KAATSU RT) on muscle strength and size in patients early after cardiac surgery. Cardiac patients (age 69.6 ± 12.6 years, n = 21, M = 18) were randomly assigned to the control (n = 1...

Descripción completa

Detalles Bibliográficos
Autores principales: Ogawa, Hironaga, Nakajima, Toshiaki, Shibasaki, Ikuko, Nasuno, Takahisa, Kaneda, Hiroyuki, Katayanagi, Satoshi, Ishizaka, Hayato, Mizushima, Yuta, Uematsu, Azusa, Yasuda, Tomohiro, Yagi, Hiroshi, Toyoda, Shigeru, Hortobágyi, Tibor, Mizushima, Takashi, Inoue, Teruo, Fukuda, Hirotsugu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7867301/
https://www.ncbi.nlm.nih.gov/pubmed/33540756
http://dx.doi.org/10.3390/jcm10030547
_version_ 1783648271423504384
author Ogawa, Hironaga
Nakajima, Toshiaki
Shibasaki, Ikuko
Nasuno, Takahisa
Kaneda, Hiroyuki
Katayanagi, Satoshi
Ishizaka, Hayato
Mizushima, Yuta
Uematsu, Azusa
Yasuda, Tomohiro
Yagi, Hiroshi
Toyoda, Shigeru
Hortobágyi, Tibor
Mizushima, Takashi
Inoue, Teruo
Fukuda, Hirotsugu
author_facet Ogawa, Hironaga
Nakajima, Toshiaki
Shibasaki, Ikuko
Nasuno, Takahisa
Kaneda, Hiroyuki
Katayanagi, Satoshi
Ishizaka, Hayato
Mizushima, Yuta
Uematsu, Azusa
Yasuda, Tomohiro
Yagi, Hiroshi
Toyoda, Shigeru
Hortobágyi, Tibor
Mizushima, Takashi
Inoue, Teruo
Fukuda, Hirotsugu
author_sort Ogawa, Hironaga
collection PubMed
description We examined the safety and the effects of low-intensity resistance training (RT) with moderate blood flow restriction (KAATSU RT) on muscle strength and size in patients early after cardiac surgery. Cardiac patients (age 69.6 ± 12.6 years, n = 21, M = 18) were randomly assigned to the control (n = 10) and the KAATSU RT group (n = 11). All patients had received a standard aerobic cardiac rehabilitation program. The KAATSU RT group additionally executed low-intensity leg extension and leg press exercises with moderate blood flow restriction twice a week for 3 months. RT-intensity and volume were increased gradually. We evaluated the anterior mid-thigh thickness (MTH), skeletal muscle mass index (SMI), handgrip strength, knee extensor strength, and walking speed at baseline, 5–7 days after cardiac surgery, and after 3 months. A physician monitored the electrocardiogram, rate of perceived exertion, and the color of the lower limbs during KAATSU RT. Creatine phosphokinase (CPK) and D-dimer were measured at baseline and after 3 months. There were no side effects during KAATSU RT. CPK and D-dimer were normal after 3 months. MTH, SMI, walking speed, and knee extensor strength increased after 3 months with KAATSU RT compared with baseline. Relatively low vs. high physical functioning patients tended to increase physical function more after 3 months with KAATSU RT. Low-intensity KAATSU RT as an adjuvant to standard cardiac rehabilitation can safely increase skeletal muscle strength and size in cardiovascular surgery patients.
format Online
Article
Text
id pubmed-7867301
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-78673012021-02-07 Low-Intensity Resistance Training with Moderate Blood Flow Restriction Appears Safe and Increases Skeletal Muscle Strength and Size in Cardiovascular Surgery Patients: A Pilot Study Ogawa, Hironaga Nakajima, Toshiaki Shibasaki, Ikuko Nasuno, Takahisa Kaneda, Hiroyuki Katayanagi, Satoshi Ishizaka, Hayato Mizushima, Yuta Uematsu, Azusa Yasuda, Tomohiro Yagi, Hiroshi Toyoda, Shigeru Hortobágyi, Tibor Mizushima, Takashi Inoue, Teruo Fukuda, Hirotsugu J Clin Med Article We examined the safety and the effects of low-intensity resistance training (RT) with moderate blood flow restriction (KAATSU RT) on muscle strength and size in patients early after cardiac surgery. Cardiac patients (age 69.6 ± 12.6 years, n = 21, M = 18) were randomly assigned to the control (n = 10) and the KAATSU RT group (n = 11). All patients had received a standard aerobic cardiac rehabilitation program. The KAATSU RT group additionally executed low-intensity leg extension and leg press exercises with moderate blood flow restriction twice a week for 3 months. RT-intensity and volume were increased gradually. We evaluated the anterior mid-thigh thickness (MTH), skeletal muscle mass index (SMI), handgrip strength, knee extensor strength, and walking speed at baseline, 5–7 days after cardiac surgery, and after 3 months. A physician monitored the electrocardiogram, rate of perceived exertion, and the color of the lower limbs during KAATSU RT. Creatine phosphokinase (CPK) and D-dimer were measured at baseline and after 3 months. There were no side effects during KAATSU RT. CPK and D-dimer were normal after 3 months. MTH, SMI, walking speed, and knee extensor strength increased after 3 months with KAATSU RT compared with baseline. Relatively low vs. high physical functioning patients tended to increase physical function more after 3 months with KAATSU RT. Low-intensity KAATSU RT as an adjuvant to standard cardiac rehabilitation can safely increase skeletal muscle strength and size in cardiovascular surgery patients. MDPI 2021-02-02 /pmc/articles/PMC7867301/ /pubmed/33540756 http://dx.doi.org/10.3390/jcm10030547 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Ogawa, Hironaga
Nakajima, Toshiaki
Shibasaki, Ikuko
Nasuno, Takahisa
Kaneda, Hiroyuki
Katayanagi, Satoshi
Ishizaka, Hayato
Mizushima, Yuta
Uematsu, Azusa
Yasuda, Tomohiro
Yagi, Hiroshi
Toyoda, Shigeru
Hortobágyi, Tibor
Mizushima, Takashi
Inoue, Teruo
Fukuda, Hirotsugu
Low-Intensity Resistance Training with Moderate Blood Flow Restriction Appears Safe and Increases Skeletal Muscle Strength and Size in Cardiovascular Surgery Patients: A Pilot Study
title Low-Intensity Resistance Training with Moderate Blood Flow Restriction Appears Safe and Increases Skeletal Muscle Strength and Size in Cardiovascular Surgery Patients: A Pilot Study
title_full Low-Intensity Resistance Training with Moderate Blood Flow Restriction Appears Safe and Increases Skeletal Muscle Strength and Size in Cardiovascular Surgery Patients: A Pilot Study
title_fullStr Low-Intensity Resistance Training with Moderate Blood Flow Restriction Appears Safe and Increases Skeletal Muscle Strength and Size in Cardiovascular Surgery Patients: A Pilot Study
title_full_unstemmed Low-Intensity Resistance Training with Moderate Blood Flow Restriction Appears Safe and Increases Skeletal Muscle Strength and Size in Cardiovascular Surgery Patients: A Pilot Study
title_short Low-Intensity Resistance Training with Moderate Blood Flow Restriction Appears Safe and Increases Skeletal Muscle Strength and Size in Cardiovascular Surgery Patients: A Pilot Study
title_sort low-intensity resistance training with moderate blood flow restriction appears safe and increases skeletal muscle strength and size in cardiovascular surgery patients: a pilot study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7867301/
https://www.ncbi.nlm.nih.gov/pubmed/33540756
http://dx.doi.org/10.3390/jcm10030547
work_keys_str_mv AT ogawahironaga lowintensityresistancetrainingwithmoderatebloodflowrestrictionappearssafeandincreasesskeletalmusclestrengthandsizeincardiovascularsurgerypatientsapilotstudy
AT nakajimatoshiaki lowintensityresistancetrainingwithmoderatebloodflowrestrictionappearssafeandincreasesskeletalmusclestrengthandsizeincardiovascularsurgerypatientsapilotstudy
AT shibasakiikuko lowintensityresistancetrainingwithmoderatebloodflowrestrictionappearssafeandincreasesskeletalmusclestrengthandsizeincardiovascularsurgerypatientsapilotstudy
AT nasunotakahisa lowintensityresistancetrainingwithmoderatebloodflowrestrictionappearssafeandincreasesskeletalmusclestrengthandsizeincardiovascularsurgerypatientsapilotstudy
AT kanedahiroyuki lowintensityresistancetrainingwithmoderatebloodflowrestrictionappearssafeandincreasesskeletalmusclestrengthandsizeincardiovascularsurgerypatientsapilotstudy
AT katayanagisatoshi lowintensityresistancetrainingwithmoderatebloodflowrestrictionappearssafeandincreasesskeletalmusclestrengthandsizeincardiovascularsurgerypatientsapilotstudy
AT ishizakahayato lowintensityresistancetrainingwithmoderatebloodflowrestrictionappearssafeandincreasesskeletalmusclestrengthandsizeincardiovascularsurgerypatientsapilotstudy
AT mizushimayuta lowintensityresistancetrainingwithmoderatebloodflowrestrictionappearssafeandincreasesskeletalmusclestrengthandsizeincardiovascularsurgerypatientsapilotstudy
AT uematsuazusa lowintensityresistancetrainingwithmoderatebloodflowrestrictionappearssafeandincreasesskeletalmusclestrengthandsizeincardiovascularsurgerypatientsapilotstudy
AT yasudatomohiro lowintensityresistancetrainingwithmoderatebloodflowrestrictionappearssafeandincreasesskeletalmusclestrengthandsizeincardiovascularsurgerypatientsapilotstudy
AT yagihiroshi lowintensityresistancetrainingwithmoderatebloodflowrestrictionappearssafeandincreasesskeletalmusclestrengthandsizeincardiovascularsurgerypatientsapilotstudy
AT toyodashigeru lowintensityresistancetrainingwithmoderatebloodflowrestrictionappearssafeandincreasesskeletalmusclestrengthandsizeincardiovascularsurgerypatientsapilotstudy
AT hortobagyitibor lowintensityresistancetrainingwithmoderatebloodflowrestrictionappearssafeandincreasesskeletalmusclestrengthandsizeincardiovascularsurgerypatientsapilotstudy
AT mizushimatakashi lowintensityresistancetrainingwithmoderatebloodflowrestrictionappearssafeandincreasesskeletalmusclestrengthandsizeincardiovascularsurgerypatientsapilotstudy
AT inoueteruo lowintensityresistancetrainingwithmoderatebloodflowrestrictionappearssafeandincreasesskeletalmusclestrengthandsizeincardiovascularsurgerypatientsapilotstudy
AT fukudahirotsugu lowintensityresistancetrainingwithmoderatebloodflowrestrictionappearssafeandincreasesskeletalmusclestrengthandsizeincardiovascularsurgerypatientsapilotstudy