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Development of a Single-Step Antibody–Drug Conjugate Purification Process with Membrane Chromatography

Membrane chromatography is routinely used to remove host cell proteins, viral particles, and aggregates during antibody downstream processing. The application of membrane chromatography to the field of antibody-drug conjugates (ADCs) has been applied in a limited capacity and in only specialized sce...

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Detalles Bibliográficos
Autores principales: Cordova, Juan Carlos, Sun, Sheng, Bos, Jeffrey, Thirumalairajan, Srinath, Ghone, Sanjeevani, Hirai, Miyako, Busse, Ricarda A., der Hardt, Julia S. v., Schwartz, Ian, Zhou, Jieyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7867349/
https://www.ncbi.nlm.nih.gov/pubmed/33540865
http://dx.doi.org/10.3390/jcm10030552