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Development of a Single-Step Antibody–Drug Conjugate Purification Process with Membrane Chromatography
Membrane chromatography is routinely used to remove host cell proteins, viral particles, and aggregates during antibody downstream processing. The application of membrane chromatography to the field of antibody-drug conjugates (ADCs) has been applied in a limited capacity and in only specialized sce...
Autores principales: | Cordova, Juan Carlos, Sun, Sheng, Bos, Jeffrey, Thirumalairajan, Srinath, Ghone, Sanjeevani, Hirai, Miyako, Busse, Ricarda A., der Hardt, Julia S. v., Schwartz, Ian, Zhou, Jieyu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7867349/ https://www.ncbi.nlm.nih.gov/pubmed/33540865 http://dx.doi.org/10.3390/jcm10030552 |
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