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Appendicitis during the COVID-19 lockdown: results of a multicenter analysis in Germany

PURPOSE: The COVID-19 pandemic has transformed medical care worldwide. General surgery has been affected in elective procedures, yet the implications for emergency surgery are unclear. The current study analyzes the effect of the COVID-19 lockdown in spring 2020 on appendicitis treatment in Germany....

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Autores principales: Willms, Arnulf G., Oldhafer, Karl J., Conze, Sophie, Thasler, Wolfgang E., von Schassen, Christian, Hauer, Thorsten, Huber, Tobias, Germer, Christoph-Thomas, Günster, Simone, Bulian, Dirk R., Hirche, Zarah, Filser, Jörg, Stavrou, Gregor A., Reichert, Martin, Malkomes, Patrizia, Seyfried, Steffen, Ludwig, Tobias, Hillebrecht, Hans C., Pantelis, Dimitrios, Brunner, Stefanie, Rost, Wilm, Lock, Johan F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7867500/
https://www.ncbi.nlm.nih.gov/pubmed/33550453
http://dx.doi.org/10.1007/s00423-021-02090-3
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author Willms, Arnulf G.
Oldhafer, Karl J.
Conze, Sophie
Thasler, Wolfgang E.
von Schassen, Christian
Hauer, Thorsten
Huber, Tobias
Germer, Christoph-Thomas
Günster, Simone
Bulian, Dirk R.
Hirche, Zarah
Filser, Jörg
Stavrou, Gregor A.
Reichert, Martin
Malkomes, Patrizia
Seyfried, Steffen
Ludwig, Tobias
Hillebrecht, Hans C.
Pantelis, Dimitrios
Brunner, Stefanie
Rost, Wilm
Lock, Johan F.
author_facet Willms, Arnulf G.
Oldhafer, Karl J.
Conze, Sophie
Thasler, Wolfgang E.
von Schassen, Christian
Hauer, Thorsten
Huber, Tobias
Germer, Christoph-Thomas
Günster, Simone
Bulian, Dirk R.
Hirche, Zarah
Filser, Jörg
Stavrou, Gregor A.
Reichert, Martin
Malkomes, Patrizia
Seyfried, Steffen
Ludwig, Tobias
Hillebrecht, Hans C.
Pantelis, Dimitrios
Brunner, Stefanie
Rost, Wilm
Lock, Johan F.
author_sort Willms, Arnulf G.
collection PubMed
description PURPOSE: The COVID-19 pandemic has transformed medical care worldwide. General surgery has been affected in elective procedures, yet the implications for emergency surgery are unclear. The current study analyzes the effect of the COVID-19 lockdown in spring 2020 on appendicitis treatment in Germany. METHODS: Hospitals that provided emergency surgical care during the COVID-19 lockdown were invited to participate. All patients diagnosed with appendicitis during the lockdown period (10 weeks) and, as a comparison group, patients from the same period in 2019 were analyzed. Clinical and laboratory parameters, intraoperative and pathological findings, and postoperative outcomes were analyzed. RESULTS: A total of 1915 appendectomies from 41 surgical departments in Germany were included. Compared to 2019 the number of appendectomies decreased by 13.5% (1.027 to 888, p=0.003) during the first 2020 COVID-19 lockdown. The delay between the onset of symptoms and medical consultation was substantially longer in the COVID-19 risk group and for the elderly. The rate of complicated appendicitis increased (58.2 to 64.4%), while the absolute number of complicated appendicitis decreased from 597 to 569, (p=0.012). The rate of negative appendectomies decreased significantly (6.7 to 4.6%; p=0.012). Overall postoperative morbidity and mortality, however, did not change. CONCLUSION: The COVID-19 lockdown had significant effects on abdominal emergency surgery in Germany. These seem to result from a stricter selection and a longer waiting time between the onset of symptoms and medical consultation for risk patients. However, the standard of emergency surgical care in Germany was maintained. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s00423-021-02090-3.
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spelling pubmed-78675002021-02-09 Appendicitis during the COVID-19 lockdown: results of a multicenter analysis in Germany Willms, Arnulf G. Oldhafer, Karl J. Conze, Sophie Thasler, Wolfgang E. von Schassen, Christian Hauer, Thorsten Huber, Tobias Germer, Christoph-Thomas Günster, Simone Bulian, Dirk R. Hirche, Zarah Filser, Jörg Stavrou, Gregor A. Reichert, Martin Malkomes, Patrizia Seyfried, Steffen Ludwig, Tobias Hillebrecht, Hans C. Pantelis, Dimitrios Brunner, Stefanie Rost, Wilm Lock, Johan F. Langenbecks Arch Surg Original Article PURPOSE: The COVID-19 pandemic has transformed medical care worldwide. General surgery has been affected in elective procedures, yet the implications for emergency surgery are unclear. The current study analyzes the effect of the COVID-19 lockdown in spring 2020 on appendicitis treatment in Germany. METHODS: Hospitals that provided emergency surgical care during the COVID-19 lockdown were invited to participate. All patients diagnosed with appendicitis during the lockdown period (10 weeks) and, as a comparison group, patients from the same period in 2019 were analyzed. Clinical and laboratory parameters, intraoperative and pathological findings, and postoperative outcomes were analyzed. RESULTS: A total of 1915 appendectomies from 41 surgical departments in Germany were included. Compared to 2019 the number of appendectomies decreased by 13.5% (1.027 to 888, p=0.003) during the first 2020 COVID-19 lockdown. The delay between the onset of symptoms and medical consultation was substantially longer in the COVID-19 risk group and for the elderly. The rate of complicated appendicitis increased (58.2 to 64.4%), while the absolute number of complicated appendicitis decreased from 597 to 569, (p=0.012). The rate of negative appendectomies decreased significantly (6.7 to 4.6%; p=0.012). Overall postoperative morbidity and mortality, however, did not change. CONCLUSION: The COVID-19 lockdown had significant effects on abdominal emergency surgery in Germany. These seem to result from a stricter selection and a longer waiting time between the onset of symptoms and medical consultation for risk patients. However, the standard of emergency surgical care in Germany was maintained. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s00423-021-02090-3. Springer Berlin Heidelberg 2021-02-07 2021 /pmc/articles/PMC7867500/ /pubmed/33550453 http://dx.doi.org/10.1007/s00423-021-02090-3 Text en © The Author(s), under exclusive licence to Springer-Verlag GmbH, DE part of Springer Nature 2021 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Original Article
Willms, Arnulf G.
Oldhafer, Karl J.
Conze, Sophie
Thasler, Wolfgang E.
von Schassen, Christian
Hauer, Thorsten
Huber, Tobias
Germer, Christoph-Thomas
Günster, Simone
Bulian, Dirk R.
Hirche, Zarah
Filser, Jörg
Stavrou, Gregor A.
Reichert, Martin
Malkomes, Patrizia
Seyfried, Steffen
Ludwig, Tobias
Hillebrecht, Hans C.
Pantelis, Dimitrios
Brunner, Stefanie
Rost, Wilm
Lock, Johan F.
Appendicitis during the COVID-19 lockdown: results of a multicenter analysis in Germany
title Appendicitis during the COVID-19 lockdown: results of a multicenter analysis in Germany
title_full Appendicitis during the COVID-19 lockdown: results of a multicenter analysis in Germany
title_fullStr Appendicitis during the COVID-19 lockdown: results of a multicenter analysis in Germany
title_full_unstemmed Appendicitis during the COVID-19 lockdown: results of a multicenter analysis in Germany
title_short Appendicitis during the COVID-19 lockdown: results of a multicenter analysis in Germany
title_sort appendicitis during the covid-19 lockdown: results of a multicenter analysis in germany
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7867500/
https://www.ncbi.nlm.nih.gov/pubmed/33550453
http://dx.doi.org/10.1007/s00423-021-02090-3
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