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Clinical mid-term outcomes of the Chinese-made CL-V bileaflet mechanical heart valve in Chinese patients

BACKGROUND: The CL-V full-carbon bileaflet mechanical heart valve is a novel Chinese-made prosthetic valve. This study evaluated the mid-term outcomes of the CL-V bileaflet mechanical heart valve after implantation in Chinese patients. METHODS: This study retrospectively enrolled a total of 38 conse...

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Autores principales: Qi, Liang, Liu, Shidong, Qiang, Yan, Zhao, Honglin, Liu, Ruisheng, Cheng, Dianwei, Song, Bing, Guan, Quanlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7867806/
https://www.ncbi.nlm.nih.gov/pubmed/33569180
http://dx.doi.org/10.21037/jtd-20-2644
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author Qi, Liang
Liu, Shidong
Qiang, Yan
Zhao, Honglin
Liu, Ruisheng
Cheng, Dianwei
Song, Bing
Guan, Quanlin
author_facet Qi, Liang
Liu, Shidong
Qiang, Yan
Zhao, Honglin
Liu, Ruisheng
Cheng, Dianwei
Song, Bing
Guan, Quanlin
author_sort Qi, Liang
collection PubMed
description BACKGROUND: The CL-V full-carbon bileaflet mechanical heart valve is a novel Chinese-made prosthetic valve. This study evaluated the mid-term outcomes of the CL-V bileaflet mechanical heart valve after implantation in Chinese patients. METHODS: This study retrospectively enrolled a total of 38 consecutive patients who underwent elective mechanical heart valve replacement (MHVR) with two different valve types from April 2004 and May 2010, including 18 patients with the CL-V bileaflet mechanical heart valve (44.4% male, mean age 47.4±6.2 years, mean body weight 64.7±11.9 kg) and 20 patients with the St. Jude mechanical heart valve (45.0% male, mean age 49.7±7.6 years, mean body weight 66.1±11.1 kg). All patients underwent follow-up clinical evaluations in the outpatient department at all-time points. RESULTS: No complications occurred during the mean 61.3 months follow-up time (range, 47–102 months). The cardiothoracic ratios (52.7%±4.5% vs. 50.1%±4.0%), left atrium diameter (46.5±7.6 vs. 44.8±9.3 mm), left ventricular diastolic diameter (47.6±4.9 vs. 48.2±8.5 mm) and left ventricular ejection fraction (65.4%±8.7% vs. 64.5%±8.0%) were not significantly different between the two groups (P>0.05). Transthoracic Doppler echocardiography showed that the hemodynamic indexes were not significantly different between the two groups at 1 year and 3 years (P>0.05). Furthermore, no significant differences were found between the two groups in hemocompatibility indexes at both 6 months and 3 years postoperatively (P>0.05). CONCLUSIONS: The mid-term follow-up results of the CL-V bileaflet mechanical heart valve were similar to those of the St. Jude Medical heart valve, which showed stable hemodynamics and good blood compatibility. Chinese-made CL-V bileaflet mechanical heart valves can be a substitute for St. Jude Medical heart valves, and can be widely used in cardiac surgery. TRIAL REGISTRATION: Chinese Clinical Trial Registry ChiCTR2000034158.
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spelling pubmed-78678062021-02-09 Clinical mid-term outcomes of the Chinese-made CL-V bileaflet mechanical heart valve in Chinese patients Qi, Liang Liu, Shidong Qiang, Yan Zhao, Honglin Liu, Ruisheng Cheng, Dianwei Song, Bing Guan, Quanlin J Thorac Dis Original Article BACKGROUND: The CL-V full-carbon bileaflet mechanical heart valve is a novel Chinese-made prosthetic valve. This study evaluated the mid-term outcomes of the CL-V bileaflet mechanical heart valve after implantation in Chinese patients. METHODS: This study retrospectively enrolled a total of 38 consecutive patients who underwent elective mechanical heart valve replacement (MHVR) with two different valve types from April 2004 and May 2010, including 18 patients with the CL-V bileaflet mechanical heart valve (44.4% male, mean age 47.4±6.2 years, mean body weight 64.7±11.9 kg) and 20 patients with the St. Jude mechanical heart valve (45.0% male, mean age 49.7±7.6 years, mean body weight 66.1±11.1 kg). All patients underwent follow-up clinical evaluations in the outpatient department at all-time points. RESULTS: No complications occurred during the mean 61.3 months follow-up time (range, 47–102 months). The cardiothoracic ratios (52.7%±4.5% vs. 50.1%±4.0%), left atrium diameter (46.5±7.6 vs. 44.8±9.3 mm), left ventricular diastolic diameter (47.6±4.9 vs. 48.2±8.5 mm) and left ventricular ejection fraction (65.4%±8.7% vs. 64.5%±8.0%) were not significantly different between the two groups (P>0.05). Transthoracic Doppler echocardiography showed that the hemodynamic indexes were not significantly different between the two groups at 1 year and 3 years (P>0.05). Furthermore, no significant differences were found between the two groups in hemocompatibility indexes at both 6 months and 3 years postoperatively (P>0.05). CONCLUSIONS: The mid-term follow-up results of the CL-V bileaflet mechanical heart valve were similar to those of the St. Jude Medical heart valve, which showed stable hemodynamics and good blood compatibility. Chinese-made CL-V bileaflet mechanical heart valves can be a substitute for St. Jude Medical heart valves, and can be widely used in cardiac surgery. TRIAL REGISTRATION: Chinese Clinical Trial Registry ChiCTR2000034158. AME Publishing Company 2021-01 /pmc/articles/PMC7867806/ /pubmed/33569180 http://dx.doi.org/10.21037/jtd-20-2644 Text en 2021 Journal of Thoracic Disease. All rights reserved. https://creativecommons.org/licenses/by-nc-nd/4.0/Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) .
spellingShingle Original Article
Qi, Liang
Liu, Shidong
Qiang, Yan
Zhao, Honglin
Liu, Ruisheng
Cheng, Dianwei
Song, Bing
Guan, Quanlin
Clinical mid-term outcomes of the Chinese-made CL-V bileaflet mechanical heart valve in Chinese patients
title Clinical mid-term outcomes of the Chinese-made CL-V bileaflet mechanical heart valve in Chinese patients
title_full Clinical mid-term outcomes of the Chinese-made CL-V bileaflet mechanical heart valve in Chinese patients
title_fullStr Clinical mid-term outcomes of the Chinese-made CL-V bileaflet mechanical heart valve in Chinese patients
title_full_unstemmed Clinical mid-term outcomes of the Chinese-made CL-V bileaflet mechanical heart valve in Chinese patients
title_short Clinical mid-term outcomes of the Chinese-made CL-V bileaflet mechanical heart valve in Chinese patients
title_sort clinical mid-term outcomes of the chinese-made cl-v bileaflet mechanical heart valve in chinese patients
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7867806/
https://www.ncbi.nlm.nih.gov/pubmed/33569180
http://dx.doi.org/10.21037/jtd-20-2644
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