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An enhanced level of LAMP-2A participates in CD4(+)T cell hyperactivity in patients with primary biliary cholangitis
BACKGROUND: Primary biliary cholangitis (PBC) is an immune-mediated chronic cholestasis, in which T cell homeostasis plays an important role. Lysosomal-associated membrane protein 2 isoform A (LAMP-2A) has been implicated in the regulation of CD4(+)T cell responses. METHODS: We comprehensively evalu...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7867869/ https://www.ncbi.nlm.nih.gov/pubmed/33569403 http://dx.doi.org/10.21037/atm-20-2427 |