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Mechanisms underlying pro-arrhythmic abnormalities arising from Pitx2-induced electrical remodelling: an in silico intersubject variability study

BACKGROUND: Electrical remodelling as a result of the homeodomain transcription factor 2 (Pitx2)-dependent gene regulation induces atrial fibrillation (AF) with different mechanisms. The purpose of this study was to identify Pitx2-induced changes in ionic currents that cause action potential (AP) sh...

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Detalles Bibliográficos
Autores principales:	Zhu, Yijie, Bai, Jieyun, Lo, Andy, Lu, Yaosheng, Zhao, Jichao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AME Publishing Company 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7867875/ https://www.ncbi.nlm.nih.gov/pubmed/33569408 http://dx.doi.org/10.21037/atm-20-5660

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