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Standardization of pleural effusion-based tumor mutation burden (TMB) estimation using capture-based targeted sequencing
BACKGROUND: Tumor mutation burden (TMB) has received considerable attention as a potential predictive biomarker for response to anticancer treatment with immune checkpoint inhibitors (ICIs), and has been increasingly incorporated into clinical practice. Currently, TMB is often determined with tissue...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
AME Publishing Company
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7867960/ https://www.ncbi.nlm.nih.gov/pubmed/33569442 http://dx.doi.org/10.21037/atm-20-7702 |