Pyrvinium pamoate inhibits cell proliferation through ROS-mediated AKT-dependent signaling pathway in colorectal cancer

The use of the anthelmintic drug pyrvinium pamoate (PP) in cancer therapy has been extensively investigated in the last decade. PP has been shown to have an inhibitory effect in colorectal cancer (CRC), but the underlying mechanism remains elusive. We aimed to investigate the antitumor activity and...

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Detalles Bibliográficos
Autores principales: Zheng, Wenqian, Hu, Jinhui, Lv, Yiming, Bai, Bingjun, Shan, Lina, Chen, Kangke, Dai, Sheng, Zhu, Hongbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7868320/
https://www.ncbi.nlm.nih.gov/pubmed/33554313
http://dx.doi.org/10.1007/s12032-021-01472-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7868320/
https://www.ncbi.nlm.nih.gov/pubmed/33554313
http://dx.doi.org/10.1007/s12032-021-01472-3

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