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Creatinine Trends to Detect Ibuprofen-Related Maturational Adverse Drug Events in Neonatal Life: A Simulation Study for the ELBW Newborn

Background: Recognizing a change in serum creatinine concentrations is useful to detect a renal adverse drug reaction signal. Assessing and characterizing the nephrotoxic side-effects of drugs in extremely low birth weight (ELBW, ≤1000 g) neonates remain challenging due to the high variability in cr...

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Detalles Bibliográficos
Autores principales:	van Donge, Tamara, Allegaert, Karel, Pfister, Marc, Smits, Anne, van den Anker, John
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7868337/ https://www.ncbi.nlm.nih.gov/pubmed/33569003 http://dx.doi.org/10.3389/fphar.2020.610294

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