Pivotal Role of TGF-β/Smad Signaling in Cardiac Fibrosis: Non-coding RNAs as Effectual Players

Unintended cardiac fibroblast proliferation in many pathophysiological heart conditions, known as cardiac fibrosis, results in pooling of extracellular matrix (ECM) proteins in the heart muscle. Transforming growth factor β (TGF-β) as a pivotal cytokine/growth factor stimulates fibroblasts and haste...

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Detalles Bibliográficos
Autores principales: Saadat, Somayeh, Noureddini, Mahdi, Mahjoubin-Tehran, Maryam, Nazemi, Sina, Shojaie, Layla, Aschner, Michael, Maleki, Behnaz, Abbasi-kolli, Mohammad, Rajabi Moghadam, Hasan, Alani, Behrang, Mirzaei, Hamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7868343/
https://www.ncbi.nlm.nih.gov/pubmed/33569393
http://dx.doi.org/10.3389/fcvm.2020.588347

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