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Respiratory Modalities in Preventing Reintubation in a Pediatric Intensive Care Unit

Post-extubation respiratory failure requiring reintubation in a Pediatric Intensive Care Unit (PICU) results in significant morbidity. Data in the pediatric population comparing various therapeutic respiratory modalities for avoiding reintubation is lacking. Our objective was to compare therapeutic...

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Autores principales: Al-Hadidi, Ameer, Lapkus, Morta, Karabon, Patrick, Akay, Begum, Khandhar, Paras
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7868480/
https://www.ncbi.nlm.nih.gov/pubmed/33614852
http://dx.doi.org/10.1177/2333794X21991531
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author Al-Hadidi, Ameer
Lapkus, Morta
Karabon, Patrick
Akay, Begum
Khandhar, Paras
author_facet Al-Hadidi, Ameer
Lapkus, Morta
Karabon, Patrick
Akay, Begum
Khandhar, Paras
author_sort Al-Hadidi, Ameer
collection PubMed
description Post-extubation respiratory failure requiring reintubation in a Pediatric Intensive Care Unit (PICU) results in significant morbidity. Data in the pediatric population comparing various therapeutic respiratory modalities for avoiding reintubation is lacking. Our objective was to compare therapeutic respiratory modalities following extubation from mechanical ventilation. About 491 children admitted to a single-center PICU requiring mechanical ventilation from January 2010 through December 2017 were retrospectively reviewed. Therapeutic respiratory support assisted in avoiding reintubation in the majority of patients initially extubated to room air or nasal cannula with high-flow nasal cannula (80%) or noninvasive positive pressure ventilation (100%). Patients requiring therapeutic respiratory support had longer PICU LOS (10.92 vs 6.91 days, P-value = .0357) and hospital LOS (16.43 vs 10.20 days, P-value = .0250). Therapeutic respiratory support following extubation can assist in avoiding reintubation. Those who required therapeutic respiratory support experienced a significantly longer PICU and hospital LOS. Further prospective clinical trials are warranted.
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spelling pubmed-78684802021-02-19 Respiratory Modalities in Preventing Reintubation in a Pediatric Intensive Care Unit Al-Hadidi, Ameer Lapkus, Morta Karabon, Patrick Akay, Begum Khandhar, Paras Glob Pediatr Health Original Research Article Post-extubation respiratory failure requiring reintubation in a Pediatric Intensive Care Unit (PICU) results in significant morbidity. Data in the pediatric population comparing various therapeutic respiratory modalities for avoiding reintubation is lacking. Our objective was to compare therapeutic respiratory modalities following extubation from mechanical ventilation. About 491 children admitted to a single-center PICU requiring mechanical ventilation from January 2010 through December 2017 were retrospectively reviewed. Therapeutic respiratory support assisted in avoiding reintubation in the majority of patients initially extubated to room air or nasal cannula with high-flow nasal cannula (80%) or noninvasive positive pressure ventilation (100%). Patients requiring therapeutic respiratory support had longer PICU LOS (10.92 vs 6.91 days, P-value = .0357) and hospital LOS (16.43 vs 10.20 days, P-value = .0250). Therapeutic respiratory support following extubation can assist in avoiding reintubation. Those who required therapeutic respiratory support experienced a significantly longer PICU and hospital LOS. Further prospective clinical trials are warranted. SAGE Publications 2021-01-27 /pmc/articles/PMC7868480/ /pubmed/33614852 http://dx.doi.org/10.1177/2333794X21991531 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Original Research Article
Al-Hadidi, Ameer
Lapkus, Morta
Karabon, Patrick
Akay, Begum
Khandhar, Paras
Respiratory Modalities in Preventing Reintubation in a Pediatric Intensive Care Unit
title Respiratory Modalities in Preventing Reintubation in a Pediatric Intensive Care Unit
title_full Respiratory Modalities in Preventing Reintubation in a Pediatric Intensive Care Unit
title_fullStr Respiratory Modalities in Preventing Reintubation in a Pediatric Intensive Care Unit
title_full_unstemmed Respiratory Modalities in Preventing Reintubation in a Pediatric Intensive Care Unit
title_short Respiratory Modalities in Preventing Reintubation in a Pediatric Intensive Care Unit
title_sort respiratory modalities in preventing reintubation in a pediatric intensive care unit
topic Original Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7868480/
https://www.ncbi.nlm.nih.gov/pubmed/33614852
http://dx.doi.org/10.1177/2333794X21991531
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