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Recent Advances in Camel Immunology
Camels are domesticated animals that are highly adapted to the extreme desert ecosystem with relatively higher resistance to a wide range of pathogens compared to many other species from the same geographical region. Recently, there has been increased interest in the field of camel immunology. As th...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7868527/ https://www.ncbi.nlm.nih.gov/pubmed/33569060 http://dx.doi.org/10.3389/fimmu.2020.614150 |
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author | Hussen, Jamal Schuberth, Hans-Joachim |
author_facet | Hussen, Jamal Schuberth, Hans-Joachim |
author_sort | Hussen, Jamal |
collection | PubMed |
description | Camels are domesticated animals that are highly adapted to the extreme desert ecosystem with relatively higher resistance to a wide range of pathogens compared to many other species from the same geographical region. Recently, there has been increased interest in the field of camel immunology. As the progress in the analysis of camel immunoglobulins has previously been covered in many recent reviews, this review intends to summarize published findings related to camel cellular immunology with a focus on the phenotype and functionality of camel leukocyte subpopulations. The review also describes the impact of different physiological (age and pregnancy) and pathological (e.g. infection) conditions on camel immune cells. Despite the progress achieved in the field of camel immunology, there are gaps in our complete understanding of the camel immune system. Questions remain regarding innate recognition mechanisms, the functional characterization of antigen-presenting cells, and the characterization of camel NK and cytotoxic T cells. |
format | Online Article Text |
id | pubmed-7868527 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-78685272021-02-09 Recent Advances in Camel Immunology Hussen, Jamal Schuberth, Hans-Joachim Front Immunol Immunology Camels are domesticated animals that are highly adapted to the extreme desert ecosystem with relatively higher resistance to a wide range of pathogens compared to many other species from the same geographical region. Recently, there has been increased interest in the field of camel immunology. As the progress in the analysis of camel immunoglobulins has previously been covered in many recent reviews, this review intends to summarize published findings related to camel cellular immunology with a focus on the phenotype and functionality of camel leukocyte subpopulations. The review also describes the impact of different physiological (age and pregnancy) and pathological (e.g. infection) conditions on camel immune cells. Despite the progress achieved in the field of camel immunology, there are gaps in our complete understanding of the camel immune system. Questions remain regarding innate recognition mechanisms, the functional characterization of antigen-presenting cells, and the characterization of camel NK and cytotoxic T cells. Frontiers Media S.A. 2021-01-25 /pmc/articles/PMC7868527/ /pubmed/33569060 http://dx.doi.org/10.3389/fimmu.2020.614150 Text en Copyright © 2021 Hussen and Schuberth http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Immunology Hussen, Jamal Schuberth, Hans-Joachim Recent Advances in Camel Immunology |
title | Recent Advances in Camel Immunology |
title_full | Recent Advances in Camel Immunology |
title_fullStr | Recent Advances in Camel Immunology |
title_full_unstemmed | Recent Advances in Camel Immunology |
title_short | Recent Advances in Camel Immunology |
title_sort | recent advances in camel immunology |
topic | Immunology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7868527/ https://www.ncbi.nlm.nih.gov/pubmed/33569060 http://dx.doi.org/10.3389/fimmu.2020.614150 |
work_keys_str_mv | AT hussenjamal recentadvancesincamelimmunology AT schuberthhansjoachim recentadvancesincamelimmunology |