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Molar Changes With a Normal Viable Fetus: A Case Report
Objective: The presence of a normal fetus with normal karyotype accompanied by molar changes in the placenta is a rare condition, which carries a significant risk to the mother and fetus. There is a controversy regarding the proper management of this condition. Here, we present the case of a singlet...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Tehran University of Medical Sciences
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7868656/ https://www.ncbi.nlm.nih.gov/pubmed/33603814 http://dx.doi.org/10.18502/jfrh.v14i3.4675 |
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author | Farazestanian, Marjaneh Maleki, Asieh Bolandi, Somayeh Yousefi, Zohreh Hasanzadeh, Malihe Shirinzadeh, Laya Kamandi, Sara |
author_facet | Farazestanian, Marjaneh Maleki, Asieh Bolandi, Somayeh Yousefi, Zohreh Hasanzadeh, Malihe Shirinzadeh, Laya Kamandi, Sara |
author_sort | Farazestanian, Marjaneh |
collection | PubMed |
description | Objective: The presence of a normal fetus with normal karyotype accompanied by molar changes in the placenta is a rare condition, which carries a significant risk to the mother and fetus. There is a controversy regarding the proper management of this condition. Here, we present the case of a singleton pregnancy that showed molar changes in the pathological study of the placenta, but ended up with a normal viable neonate. Case Report: A 23-year-old primigravida woman, with a 3-year history of infertility, presented with vaginal bleeding and spotting. Her ß-human chorionic gonadotropin (HCG) at 13(th) week was 36500 mIU/ml. Serial sonography assessments were suggestive for molar changes and a normal fetus with growth retardation but normal Doppler assessment. The patient underwent elective Cesarean section at 37 weeks gestation and a healthy female neonate with an Apgar score of 9-10, weighing 2270 g was born. Pathological assessment of the placenta confirmed the diagnosis of incomplete hydatidiform mole. After two months, the mother had no complications, her ß-HCG level was untraceable, and the infant was in good condition. Conclusion: Despite being a rare condition, partial moles can be accompanied by delivery of a normal fetus. The management of this condition still remains challenging and should be done under close monitoring with extreme caution. |
format | Online Article Text |
id | pubmed-7868656 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Tehran University of Medical Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-78686562021-02-17 Molar Changes With a Normal Viable Fetus: A Case Report Farazestanian, Marjaneh Maleki, Asieh Bolandi, Somayeh Yousefi, Zohreh Hasanzadeh, Malihe Shirinzadeh, Laya Kamandi, Sara J Family Reprod Health Case Report Objective: The presence of a normal fetus with normal karyotype accompanied by molar changes in the placenta is a rare condition, which carries a significant risk to the mother and fetus. There is a controversy regarding the proper management of this condition. Here, we present the case of a singleton pregnancy that showed molar changes in the pathological study of the placenta, but ended up with a normal viable neonate. Case Report: A 23-year-old primigravida woman, with a 3-year history of infertility, presented with vaginal bleeding and spotting. Her ß-human chorionic gonadotropin (HCG) at 13(th) week was 36500 mIU/ml. Serial sonography assessments were suggestive for molar changes and a normal fetus with growth retardation but normal Doppler assessment. The patient underwent elective Cesarean section at 37 weeks gestation and a healthy female neonate with an Apgar score of 9-10, weighing 2270 g was born. Pathological assessment of the placenta confirmed the diagnosis of incomplete hydatidiform mole. After two months, the mother had no complications, her ß-HCG level was untraceable, and the infant was in good condition. Conclusion: Despite being a rare condition, partial moles can be accompanied by delivery of a normal fetus. The management of this condition still remains challenging and should be done under close monitoring with extreme caution. Tehran University of Medical Sciences 2020-09 /pmc/articles/PMC7868656/ /pubmed/33603814 http://dx.doi.org/10.18502/jfrh.v14i3.4675 Text en Copyright © 2020 Tehran University of Medical Sciences. This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International license, (https://creativecommons.org/licenses/by-nc/4.0/) Non-commercial uses of the work are permitted, provided the original work is properly cited. |
spellingShingle | Case Report Farazestanian, Marjaneh Maleki, Asieh Bolandi, Somayeh Yousefi, Zohreh Hasanzadeh, Malihe Shirinzadeh, Laya Kamandi, Sara Molar Changes With a Normal Viable Fetus: A Case Report |
title | Molar Changes With a Normal Viable Fetus: A Case Report |
title_full | Molar Changes With a Normal Viable Fetus: A Case Report |
title_fullStr | Molar Changes With a Normal Viable Fetus: A Case Report |
title_full_unstemmed | Molar Changes With a Normal Viable Fetus: A Case Report |
title_short | Molar Changes With a Normal Viable Fetus: A Case Report |
title_sort | molar changes with a normal viable fetus: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7868656/ https://www.ncbi.nlm.nih.gov/pubmed/33603814 http://dx.doi.org/10.18502/jfrh.v14i3.4675 |
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