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Molar Changes With a Normal Viable Fetus: A Case Report

Objective: The presence of a normal fetus with normal karyotype accompanied by molar changes in the placenta is a rare condition, which carries a significant risk to the mother and fetus. There is a controversy regarding the proper management of this condition. Here, we present the case of a singlet...

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Autores principales: Farazestanian, Marjaneh, Maleki, Asieh, Bolandi, Somayeh, Yousefi, Zohreh, Hasanzadeh, Malihe, Shirinzadeh, Laya, Kamandi, Sara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tehran University of Medical Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7868656/
https://www.ncbi.nlm.nih.gov/pubmed/33603814
http://dx.doi.org/10.18502/jfrh.v14i3.4675
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author Farazestanian, Marjaneh
Maleki, Asieh
Bolandi, Somayeh
Yousefi, Zohreh
Hasanzadeh, Malihe
Shirinzadeh, Laya
Kamandi, Sara
author_facet Farazestanian, Marjaneh
Maleki, Asieh
Bolandi, Somayeh
Yousefi, Zohreh
Hasanzadeh, Malihe
Shirinzadeh, Laya
Kamandi, Sara
author_sort Farazestanian, Marjaneh
collection PubMed
description Objective: The presence of a normal fetus with normal karyotype accompanied by molar changes in the placenta is a rare condition, which carries a significant risk to the mother and fetus. There is a controversy regarding the proper management of this condition. Here, we present the case of a singleton pregnancy that showed molar changes in the pathological study of the placenta, but ended up with a normal viable neonate. Case Report: A 23-year-old primigravida woman, with a 3-year history of infertility, presented with vaginal bleeding and spotting. Her ß-human chorionic gonadotropin (HCG) at 13(th) week was 36500 mIU/ml. Serial sonography assessments were suggestive for molar changes and a normal fetus with growth retardation but normal Doppler assessment. The patient underwent elective Cesarean section at 37 weeks gestation and a healthy female neonate with an Apgar score of 9-10, weighing 2270 g was born. Pathological assessment of the placenta confirmed the diagnosis of incomplete hydatidiform mole. After two months, the mother had no complications, her ß-HCG level was untraceable, and the infant was in good condition. Conclusion: Despite being a rare condition, partial moles can be accompanied by delivery of a normal fetus. The management of this condition still remains challenging and should be done under close monitoring with extreme caution.
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spelling pubmed-78686562021-02-17 Molar Changes With a Normal Viable Fetus: A Case Report Farazestanian, Marjaneh Maleki, Asieh Bolandi, Somayeh Yousefi, Zohreh Hasanzadeh, Malihe Shirinzadeh, Laya Kamandi, Sara J Family Reprod Health Case Report Objective: The presence of a normal fetus with normal karyotype accompanied by molar changes in the placenta is a rare condition, which carries a significant risk to the mother and fetus. There is a controversy regarding the proper management of this condition. Here, we present the case of a singleton pregnancy that showed molar changes in the pathological study of the placenta, but ended up with a normal viable neonate. Case Report: A 23-year-old primigravida woman, with a 3-year history of infertility, presented with vaginal bleeding and spotting. Her ß-human chorionic gonadotropin (HCG) at 13(th) week was 36500 mIU/ml. Serial sonography assessments were suggestive for molar changes and a normal fetus with growth retardation but normal Doppler assessment. The patient underwent elective Cesarean section at 37 weeks gestation and a healthy female neonate with an Apgar score of 9-10, weighing 2270 g was born. Pathological assessment of the placenta confirmed the diagnosis of incomplete hydatidiform mole. After two months, the mother had no complications, her ß-HCG level was untraceable, and the infant was in good condition. Conclusion: Despite being a rare condition, partial moles can be accompanied by delivery of a normal fetus. The management of this condition still remains challenging and should be done under close monitoring with extreme caution. Tehran University of Medical Sciences 2020-09 /pmc/articles/PMC7868656/ /pubmed/33603814 http://dx.doi.org/10.18502/jfrh.v14i3.4675 Text en Copyright © 2020 Tehran University of Medical Sciences. This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International license, (https://creativecommons.org/licenses/by-nc/4.0/) Non-commercial uses of the work are permitted, provided the original work is properly cited.
spellingShingle Case Report
Farazestanian, Marjaneh
Maleki, Asieh
Bolandi, Somayeh
Yousefi, Zohreh
Hasanzadeh, Malihe
Shirinzadeh, Laya
Kamandi, Sara
Molar Changes With a Normal Viable Fetus: A Case Report
title Molar Changes With a Normal Viable Fetus: A Case Report
title_full Molar Changes With a Normal Viable Fetus: A Case Report
title_fullStr Molar Changes With a Normal Viable Fetus: A Case Report
title_full_unstemmed Molar Changes With a Normal Viable Fetus: A Case Report
title_short Molar Changes With a Normal Viable Fetus: A Case Report
title_sort molar changes with a normal viable fetus: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7868656/
https://www.ncbi.nlm.nih.gov/pubmed/33603814
http://dx.doi.org/10.18502/jfrh.v14i3.4675
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