A rare case of bilateral conjunctival Kaposi's sarcoma in a HIV-negative patient

PURPOSE: Kaposi's sarcoma (KS) is a rare multi-centric vascular neoplasm, first described by Moritz Kaposi in 1872. It can appear in four different forms: classic, endemic, HIV-related and post-transplant form. We present an uncommon case of seronegative HIV infection patient with skin KS invol...

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Autores principales: Fossataro, Federica, Iuliano, Adriana, Uccello, Giovanni, Lanni, Vittoria, D'Andrea, Luca, Mascolo, Massimo, Travaglino, Antonio, Tranfa, Fausto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7868732/
https://www.ncbi.nlm.nih.gov/pubmed/33598589
http://dx.doi.org/10.1016/j.ajoc.2021.101024
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author Fossataro, Federica
Iuliano, Adriana
Uccello, Giovanni
Lanni, Vittoria
D'Andrea, Luca
Mascolo, Massimo
Travaglino, Antonio
Tranfa, Fausto
author_facet Fossataro, Federica
Iuliano, Adriana
Uccello, Giovanni
Lanni, Vittoria
D'Andrea, Luca
Mascolo, Massimo
Travaglino, Antonio
Tranfa, Fausto
author_sort Fossataro, Federica
collection PubMed
description PURPOSE: Kaposi's sarcoma (KS) is a rare multi-centric vascular neoplasm, first described by Moritz Kaposi in 1872. It can appear in four different forms: classic, endemic, HIV-related and post-transplant form. We present an uncommon case of seronegative HIV infection patient with skin KS involving conjunctiva of both eyes. OBSERVATIONS: Firstly, right eye lesions were surgically removed. Subsequently, the patient was administered with systemic chemotherapy (doxorubicin) to treat both skin and left eye lesions. No signs of recurrence were observed at 20 months’ follow-up. CONCLUSIONS: Both eyes involvement in KS is rarely described in scientific literature. Both surgery and chemotherapy could be considered valid treatment options for conjunctival KS.
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spelling pubmed-78687322021-02-16 A rare case of bilateral conjunctival Kaposi's sarcoma in a HIV-negative patient Fossataro, Federica Iuliano, Adriana Uccello, Giovanni Lanni, Vittoria D'Andrea, Luca Mascolo, Massimo Travaglino, Antonio Tranfa, Fausto Am J Ophthalmol Case Rep Case Report PURPOSE: Kaposi's sarcoma (KS) is a rare multi-centric vascular neoplasm, first described by Moritz Kaposi in 1872. It can appear in four different forms: classic, endemic, HIV-related and post-transplant form. We present an uncommon case of seronegative HIV infection patient with skin KS involving conjunctiva of both eyes. OBSERVATIONS: Firstly, right eye lesions were surgically removed. Subsequently, the patient was administered with systemic chemotherapy (doxorubicin) to treat both skin and left eye lesions. No signs of recurrence were observed at 20 months’ follow-up. CONCLUSIONS: Both eyes involvement in KS is rarely described in scientific literature. Both surgery and chemotherapy could be considered valid treatment options for conjunctival KS. Elsevier 2021-01-31 /pmc/articles/PMC7868732/ /pubmed/33598589 http://dx.doi.org/10.1016/j.ajoc.2021.101024 Text en © 2021 The Authors. Published by Elsevier Inc. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Fossataro, Federica
Iuliano, Adriana
Uccello, Giovanni
Lanni, Vittoria
D'Andrea, Luca
Mascolo, Massimo
Travaglino, Antonio
Tranfa, Fausto
A rare case of bilateral conjunctival Kaposi's sarcoma in a HIV-negative patient
title A rare case of bilateral conjunctival Kaposi's sarcoma in a HIV-negative patient
title_full A rare case of bilateral conjunctival Kaposi's sarcoma in a HIV-negative patient
title_fullStr A rare case of bilateral conjunctival Kaposi's sarcoma in a HIV-negative patient
title_full_unstemmed A rare case of bilateral conjunctival Kaposi's sarcoma in a HIV-negative patient
title_short A rare case of bilateral conjunctival Kaposi's sarcoma in a HIV-negative patient
title_sort rare case of bilateral conjunctival kaposi's sarcoma in a hiv-negative patient
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7868732/
https://www.ncbi.nlm.nih.gov/pubmed/33598589
http://dx.doi.org/10.1016/j.ajoc.2021.101024
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