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Human marginal zone B cell development from early T2 progenitors
B cells emerge from the bone marrow as transitional (TS) B cells that differentiate through T1, T2, and T3 stages to become naive B cells. We have identified a bifurcation of human B cell maturation from the T1 stage forming IgM(hi) and IgM(lo) developmental trajectories. IgM(hi) T2 cells have highe...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7868795/ https://www.ncbi.nlm.nih.gov/pubmed/33538776 http://dx.doi.org/10.1084/jem.20202001 |