Systematic memory B cell archiving and random display shape the human splenic marginal zone throughout life

Human memory B cells (MBCs) are generated and diversified in secondary lymphoid tissues throughout the organism. A paired immunoglobulin (Ig)-gene repertoire analysis of peripheral blood (PB) and splenic MBCs from infant, adult, and elderly humans revealed that throughout life, circulating MBCs are...

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Detalles Bibliográficos
Autores principales: Kibler, Artur, Budeus, Bettina, Homp, Ekaterina, Bronischewski, Kevin, Berg, Victoria, Sellmann, Ludger, Murke, Florian, Heinold, Andreas, Heinemann, Falko M., Lindemann, Monika, Bekeredjian-Ding, Isabelle, Horn, Peter A., Kirschning, Carsten J., Küppers, Ralf, Seifert, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7868796/
https://www.ncbi.nlm.nih.gov/pubmed/33538775
http://dx.doi.org/10.1084/jem.20201952

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