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Smudge cells due to infectious mononucleosis

The smudge cells are well studied as a prognostic factor for chronic lymphocytic leukemia, but it is also found in viral infections. We experienced a case of abnormal hyperleukocytosis (WBC 41,600/mm3) associated with infectious mononucleosis (IM). The smudge cells were observed in peripheral blood...

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Detalles Bibliográficos
Autores principales: Higuchi, Toru, Eiki, Ogawa, Hiroshi, Hamashima, Kenta, Ito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7868801/
https://www.ncbi.nlm.nih.gov/pubmed/33598404
http://dx.doi.org/10.1016/j.idcr.2021.e01057
Descripción
Sumario:The smudge cells are well studied as a prognostic factor for chronic lymphocytic leukemia, but it is also found in viral infections. We experienced a case of abnormal hyperleukocytosis (WBC 41,600/mm3) associated with infectious mononucleosis (IM). The smudge cells were observed in peripheral blood smears, and were counted by mistake for the normal lymphocytes by the automatic blood count meter.