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Targeting NF-κB mediated cell signaling pathway and inflammatory mediators by 1,2-diazole in A549 cells in vitro
Lung cancer is the leading cause of cancer deaths globally. The objective of this study was to investigate the effect of 1,2-diazole (pyrazole) as an anti-cancer drug on human non-small cell lung carcinoma A549 cells. We attempt to examine the expression level of pro-inflammatory proteins such as TN...
Autores principales: | Vinod Prabhu, Venugopal, Elangovan, Perumal, Niranjali Devaraj, Sivasithambaram, Sakthivel, Kunnathur Murugesan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7868824/ https://www.ncbi.nlm.nih.gov/pubmed/33598414 http://dx.doi.org/10.1016/j.btre.2021.e00594 |
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