Combining vanadyl sulfate with Newcastle disease virus potentiates rapid innate immune-mediated regression with curative potential in murine cancer models

The avian paramyxovirus, Newcastle disease virus (NDV), is a promising oncolytic agent that has been shown to be safe and effective in a variety of pre-clinical cancer models and human clinical trials. NDV preferentially replicates in tumor cells due to signaling defects in apoptotic and antiviral p...

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Detalles Bibliográficos
Autores principales: McAusland, Thomas M., van Vloten, Jacob P., Santry, Lisa A., Guilleman, Matthew M., Rghei, Amira D., Ferreira, Edgar M., Ingrao, Joelle C., Arulanandam, Rozanne, Major, Pierre P., Susta, Leonardo, Karimi, Khalil, Diallo, Jean-Simon, Bridle, Byram W., Wootton, Sarah K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7868934/
https://www.ncbi.nlm.nih.gov/pubmed/33614913
http://dx.doi.org/10.1016/j.omto.2021.01.009

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