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Celastrol inhibits intestinal lipid absorption by reprofiling the gut microbiota to attenuate high-fat diet-induced obesity
Celastrol, a compound extracted from traditional Chinese medicine, has been reported as a potent anti-obesity agent with controversial mechanisms. Here both C57BL/6J and leptin-deficient (ob/ob) mice fed a high-fat diet (HFD) displayed body weight loss after celastrol therapy, opposing the previous...
Autores principales: | Hua, Hu, Zhang, Yue, Zhao, Fei, Chen, Ke, Wu, Tong, Liu, Qianqi, Huang, Songming, Zhang, Aihua, Jia, Zhanjun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7868996/ https://www.ncbi.nlm.nih.gov/pubmed/33598642 http://dx.doi.org/10.1016/j.isci.2021.102077 |
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