miR-130a activates the VEGFR2/STAT3/HIF1α axis to potentiate the vasoregenerative capacity of endothelial colony-forming cells in hypoxia

Hypoxia modulates reparative angiogenesis, which is a tightly regulated pathophysiological process. MicroRNAs (miRNAs) are important regulators of gene expression in hypoxia and angiogenesis. However, we do not yet have a clear understanding of how hypoxia-induced miRNAs fine-tune vasoreparative pro...

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Detalles Bibliográficos
Autores principales: Guduric-Fuchs, Jasenka, Pedrini, Edoardo, Lechner, Judith, Chambers, Sarah E.J., O’Neill, Christina L., Mendes Lopes de Melo, Joana, Pathak, Varun, Church, Rachel H., McKeown, Stuart, Bojdo, James, Mcloughlin, Kiran J., Stitt, Alan W., Medina, Reinhold J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7869000/
https://www.ncbi.nlm.nih.gov/pubmed/33614244
http://dx.doi.org/10.1016/j.omtn.2021.01.015

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