GITRL on dendritic cells aggravates house dust mite-induced airway inflammation and airway hyperresponsiveness by modulating CD4(+) T cell differentiation

BACKGROUND: Glucocorticoid-induced tumor necrosis factor receptor family-related protein ligand (GITRL) plays an important role in tumors, autoimmunity and inflammation. However, GITRL is not known to modulate the pathogenesis of allergic asthma. In this study, we investigated whether regulating GIT...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Yaping, Liao, Kou, Liu, Bo, Niu, Chao, Zou, Wenjing, Yang, Lili, Wang, Ting, Tian, Daiyin, Luo, Zhengxiu, Dai, Jihong, Li, Qubei, Liu, Enmei, Gong, Caihui, Fu, Zhou, Li, Ying, Ding, Fengxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7869253/
https://www.ncbi.nlm.nih.gov/pubmed/33557842
http://dx.doi.org/10.1186/s12931-020-01583-x

Ejemplares similares

Ejemplares similares